The interaction between succinic-oligochitosan-rare earth complexes( BCS-La and BCSNd) and herring sperm DNA was investigated by cyclic voltammetry and UV-Vis spectra. The results indicated as follows. Firstly,the peak current of probe molecule Fe( CN)3/46 at Au / DNA electrodes obviously decreased and the peak potential shifted positively because of the existences of complexes. All above these showed that there was a competitive effect between complexes and probe molecule with herring sperm DNA,which revealed that a binding mode intercalation was interacted between complexes and herring sperm DNA. The reaction of Fe( CN)3/46 at Au / DNA electrodes was controlled by adsorption mechanism in the range of scan rate from 0. 01 V / s to 0. 2 V / s. Secondly,the absorption intensity of herring sperm DNA decreased with the adding of complexes,and the maximum absorption peak had a red shift,which further illustrated that a binding mode intercalation was interacted between complexes and herring sperm DNA,thus led to the change of DNA conformation. The combining ratio of n( BCS-La) and n( BCS-Nd) with DNA was 2∶ 1 and 6∶ 1,respectively.
Chinese Journal of Luminescence