The formation of the bone-like apatite containing carbonate has been deeply believed to provide the favorable environment for the new bone growth. At present, many researches have been carried out to study the calcium phosphate ceramics without carbonate. There have been few researches to focus on the carbonate-contained calcium phosphate ceramics, especially on the carbonate-contained HA/β-TCP. In this paper, the effect of the macropore diameter on the formation of the bone-like apatite in the carbonate-contained HA/β-TCP porous ceramics was discussed in detail for the first time. The results have shown that the bone-like apatite crystals can be formed in the surface and on the pore wall of this ceramics in shorter time (about 6days). And the 300～400μm macropore diameter favored the formation of the bone-like apatite crystals. The crystals were identified as the B-substituted bone-like apatite and calcium-lacked hydroxyapatite, which is beneficial to the osteoinductivity of the material. The optimization of the macropore diameter was advantageous to improving the osteoinductivity of the carbonate-contained HA/β- TCP porous ceramics, which was great help to the restoration of the bone defect.
Journal of Functional Materials
calcium phosphate ceramics