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多孔羟基磷灰石修复关节骨及软骨缺损的实验研究 预览 被引量:2

STUDY ON THE REPAIR OF DEFECTED JOINT BONE AND CARTILAGE BY POROUS HYDROXYAPATITE
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摘要 在兔股骨外侧髁外侧面,通过外科手术做一骨及软骨缺损区,将相应大小的羟基磷灰石(简称HAP)植入,用自体游离软骨膜包囊HAP朝向关节腔的一端,生发层朝向HAP,HAP外侧覆盖自体游离骨膜。通过肉眼、X光片、光镜及电镜观察,软骨膜在HAP表面生长情况及HAP与骨质愈合情况以及游离骨在HAP表面向HAP孔隙内的生长情况。实验结果表明:在关节腔内,自体游离软骨膜覆盖HAP下端充当关节面的部分,软骨膜生长良 A defect of bone and cartilage at the lateral side of the lateral femoral condyle of the rabbit was made surgically.Hydroxyapatite(HAP)of the same size was grafted.The segment of HAP toward joint cavity was wrapped with autofreeperichondrium with its cambium layer toward HAP,and the lateral side of HAP was covered by the autofreeperichondrium.The growth of perichodrium on the surface of HAP,the healing of the bone,the growth of the freeperichondrium in the small opening of HAP were observed by the naked eyes,X-ray,light and electron microscope.The results showed that the perichondrium covering segment of HAP acting the part of the articular surface grew well.The perichondrium produced new tissues towards the small opening of HAP and produced a hyaline cartilage on the articular surface.The structure around HAP could grow into spur-like structure towards the small opening of HAP. The contacted bone was bonded directly to HAP.
作者 孙吉林 王智勇 王学礼 马俊华 Sun Jilin;Wang Zhiyong(Hebei Provincial Hospital Third Affiliated Hospital)Wang Xueli;Ma Junhua(Department of Anatomy)
出处 《河北医学院学报》 1995年第5期 257-260,T007,共5页
关键词 关节缺损 软骨缺损 修复术 羟基磷灰石 关节成形 hydroxyapatite repair defect of the articular surface rabbit
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