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恶性肿瘤患者活化血小板的检测 被引量:12

Detection of Activated Platelet in Patients with Malignant Tumor
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摘要 目的:探讨恶性肿瘤患者血小板的活化状态及CD62p和CD63在恶性肿瘤患者中检测的临床意义.方法:采用流式细胞术对76例恶性肿瘤患者(未转移组45例,转移组31例)活化血小板标志物CD62p和CD63的表达进行检测,并与对照组比较.结果:恶性肿瘤患者CD62p和CD63显著高于对照组,转移组显著高于未转移组(P<0.01).结论:恶性肿瘤患者血小板处于活化状态,其活化程度与是否转移相关. Objective: To study the platelet activation in clinical value of detection of CD62p and CD63 in the patients. detect the expression of platelet activation markers CD62p and without metastasis and 31 cases with metastasis) and the results patients with malignant tumor and the Methods: Flow cytometry was used to CD63 in 76 cancer patients (45 cases were compared with the normal control group. Results: The expression of CD62p and CD63 in cancer patients was significantly higher than that of the controls (P〈0.01). The expression of CD62p and CD63 in metastasis group was significantly higher than that of the non-metastasis group. Conclusion: The platelets in cancer patients are activated. The level of activation is associated with the occurrence of metastasis.
作者 张峻梅 唐方 李玲 Zhang JunMei;Tang Fang;Li Ling
出处 《中国肿瘤临床》 CAS CSCD 北大核心 2005年第16期 920-922,共3页 Chinese Journal of Clinical Oncology
关键词 活化血小板 恶性肿瘤 流式细胞术 Activated platelet Malignant tumor Flow cytometry
作者简介 通讯作者:张峻梅zjm-bird@hotmail.com
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参考文献10

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