Objective To survey the incidence of depression in Parkinson disease （PDD） and explore the related factors of PDD. Methods 127 patients with Parkinson disease were investigated, all of them were assessed by Hamilton Depression Rating Scale, self - designed register form and the Unified Parkinson disease scale （UPDRS）. A stepwise multiple factor regression analysis was carried out to determine factors that best accounted for the occurrence of PDD. Results The overall incidence rate was 47.2%. The minor, moderate and major incidence was 14.2%, 28.3% and 4.7 % respectively. The regression analysis showed that factors accounted for the occurrence of PDD were gender, the severity of PD, stage of patient＇s motor impairment, education level and the use of dopamine agonists. Conclusion PDD seems to have a multifactorial etiology. Knowledge of risk factors related to the occurrence of PDD may help guide neurologists in the early prediction and treatment of this disease.
Chinese Journal of Practical Internal Medicine
Parkinson disease Depression Epidemiology