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窒息后新生儿血中胃泌素和胃动素水平的研究 被引量:45

Blood gastrin and motilin concentration in term newborn infants after asphyxia
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摘要 为了探讨出生窒息对新生儿消化系统的影响及其发生机理,用放射免疫法对窒息后新生儿生后喂奶前及第7天血中胃泌素、胃动素浓度进行了测定,并以正常新生儿作对照。结果:窒息后患儿生后喂奶前血清胃泌素浓度为116±7ng/L,明显低于正常对照组的135±4ng/L(P〈0.05)。而血浆胃动素浓度为431±38ng/L,明显高于对照组的304±22ng/L(P〈0.01)。窒息组生后第7日空腹血中胃泌素浓度( To investigate the impact of asphyxia on gastrointestinal tract in newborn infants with birth asphyxia, we measured serum gastrin and plasma motilin concntration via radioimmunoassay in 28 term newborns with birth asphyxia before enteral feedings and on the seventh day after birth, and compared with those of normal controls. The results showed that in newborns with birth asphyxia the level of serum gastrin decreased and the level of plasma motilin increased before enteral feeding after birth in comparison with hose of normal controls (116±7 ng/L vs. 135±4 ng/L, P <0.05 and 431±38ng/L vs. 304±22 ng/L, P <0.01,respectively). The concentrations of both hormones were enhanced on the seventh day (gastrin: 132+8 ng/L, motilin: 726±60 ng/L) in comparison with those obtained immediately after birth ( P <0.05, P <0.01). These results suggest that in neonates with birth asphyxia the change in levels of blood gastrin and motilin may be one of the pathogenic factors of some gastrointestinal symptoms.
作者 孙梅 韩玉昆 Sun Mei, Han Yukun, Zhang Hui. Department of Pediatrics, Second Clinical College, China Medical University, Shenyang 110003
出处 《中华儿科杂志》 CAS CSCD 北大核心 1997年第3期 135-137,共3页 Chinese Journal of Pediatrics
关键词 新生儿窒息 胃泌素 胃动素 Infant, newborn Asphyxia Gastrin Motilin
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参考文献2

  • 1陈宝芳,中国实用儿科杂志,1994年,9卷,98页 被引量:1
  • 2郑芝田,胃肠病学(第2版),1993年,1201页 被引量:1

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