期刊文献+

内硝基冠醚中间体的合成 预览 被引量:1

SYNTHESIS OF INTERMADIATES FOR INNER NITROCROWN ETHER
在线阅读 免费下载
收藏 分享 导出
摘要 研究了作为制备新型内硝基冠醚原料的中间体2-硝基-1,3-苯二酚及多甘醇双对甲苯磺酸酯的合成。通过改进NB的合成条件,使磺化,硝化,水解三步总收率由12.9%提高到37.5%;以吡啶为溶剂和HCl的束缚剂,控制反应物摩尔比为TsCl:OEG=2.06;1.00,在0℃-5℃反应2h后,加入适量水静置过夜,可明显提高OEDT的收率和纯度。 Synthesis of 2 nitro 1,3 benzenediol( NB) and oligoethyleneglycol ditosylate(OEDT) used as material for inner nitrocrown ether are studied. By improving the reaction conditions,the NB gross yield of three steps preparation raise from 12.9% to 37.5%.Using pyridine as solvent and HCl capture,controlling the reactants mol ratio TsCl∶OEG= 2 06∶1 00, reacting at 0℃~5℃ for 2 h,so that the yield and purity of OEDT are improved.
作者 李淑勉 李占才 Li Shumian Li Shumian place of work is Chemical Engineering Department of ZILI Li Zhancai Hou Shoujun Lu Ke Niu Hong
出处 《郑州轻工业学院学报》 1997年第2期 59-62,共4页 Journal of Zhengzhou Institute of Light Industry(Natural Science)
基金 河南省自然科学基金
关键词 硝基酚类 冠醚 中间体 合成 内硝基冠醚 nitrophends crown ethers compounds intermediate 2 nitro 1,3 benzene diol oligoethyleneglycol ditosylate inner nitrocrown ether
  • 相关文献

参考文献3

共引文献7

同被引文献9

  • 1[1]Sarwar M, Rashid A, Zaidi S. A new acid base indicator:Its pKa and pT values[J]. Pak J Sci Ind Res, 1997, 20(1): 57-59. 被引量:1
  • 2[2]Rose D, Lieske E, Hoeffkes H. Oxidative hair dyes containing nitrobenzene coupling agents[P]. Ger Offen:DE 4011481 A1, 1991-10-10. 被引量:1
  • 3[3]Manieh A, Sayed A Z. Preparation of new acid dyes from toluene derivatives and study of their dyeing properties on wool[J]. Al-Azhar Bull Sci, 1995, 6(1): 35-48. 被引量:1
  • 4[4]Manieh A, Sayed A Z. Some new dyes from 4-methyl-aniline-3-sulfone-2-toluidine[J]. Al-Azhar Bull Sci, 1995, 6(1): 49-60. 被引量:1
  • 5[5]Ando K Yagihara M, Naruse H. Processing of color photographic materials with developing bath free of benzyl alcohol[P]. Jpn: Kokai Tokkyo Koho JP 63044656 A2, 1988-02-25. 被引量:1
  • 6[6]Richards T P, Hamilton A D. π-Acceptor macrocycles: new crown ethers containing isocyanide groups[J]. J Chem Soc Chem Commun, 1985(17): 1198-1199. 被引量:1
  • 7王德玢,蒋培华,胡宏纹.2'-羟基-1',3'-苯撑二亚甲基冠醚的合成[J].高等学校化学学报,1985,6(1):45-48. 被引量:1
  • 8[8]Saari W S, Wai J S, Fisher T E, et al. Synthesis and eveluation of 2-pyridinon derivatives as HIV-1-specific reverse transcriptase inhibitors Analogs of 3-aminopyridin-2(1H)-one[J]. J Med Chem, 1992, 35(21): 3792-802. 被引量:1
  • 9[10]Cadogan J I G, Ley S V, Pattenden G, et al. Dictionary of Organic Compounds. Sixth Edition[M]. London: Published by Chapman & Hall,1996. 被引量:1

引证文献1

二级引证文献1

投稿分析

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部 意见反馈