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不同剂量地塞米松混合湿敷液预防儿童静脉炎的疗效 预览

Comparison of efficacy on prevention of child phlebitis with different doses of dexamethasone in hydropathic liquid
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摘要 目的选择静脉炎预防药物的最佳浓度匹配,来降低静脉炎的发生,为长期需要化疗的患儿减轻痛苦。方法选择2%利多卡因5mL+25%硫酸镁15mL+地塞米松2.5mg同步化疗前静脉湿敷为实验组①,2%利多卡因5mL+25%硫酸镁15mL+地塞米松5mg同步化疗前静脉湿敷为实验组②,常规化疗不使用同步化疗前药物湿敷静脉为观察组。结果实验组①与观察组比较和实验组②与观察组比较差异均有统计学意义(P〈0.01);实验组①湿敷疗效高于实验组②,P〈0.05。结论用2%利多卡因及25%硫酸镁联合地塞米松可以很好地预防静脉炎发生;2%利多卡因5mL+25%硫酸镁15mL+地塞米松2.5mg比2%利多卡因5mL+25%硫酸镁15mL+地塞米松5mg湿敷预防静脉炎效果更显著;有利于患儿化疗的顺利进行并有效减轻了痛苦。 Objective To reduce the incidence of phlebitis during long course of chemotherapy in leuke- mic child patients by the choice of the best concentration of ingredients in the hydropathic liquid. Methods For experimental group 1, hydropathic compress with 2% lidoeaine 5 mL + 25% magnesium sulfate 15 mL +2.5 mg dexamethasone was applied to the candidate vein before chemotherapy. And for experi-mental group 2, 2% lidocaine 5 mL + 25% magnesium sulfate 15 mL + 5 mg dexamethasone compress was used. For the control group, no hydropathic compress was used before chemotherapy. Results There were signifieantl difference of efficacy in experimental group 1 and 2 as compared to the control group (P〈0.01). The efficacy of experimental group 1 was higher than that of experimental group 2, (P〈0.05). Conclusion Hydropathic compress with 2% lidocaine +25% magnesium sulfate + dexa- methasone can be used to prevent the development of phlebitis caused by chemotherapy; 2.5mg dexam- ethasone has better effect than that of 5 mg.
作者 张齐放 李晶晶 秦彬 ZHANG Qi-fang, LI Jing-jing, QIN Bin( Ruifin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200025, China)
出处 《上海护理》 2009年第3期 8-10,共3页 Shanghai Nursing Journal
基金 上海交通大学医学院科技基金项目(jyh0805).
关键词 化疗 静脉炎 湿敷液 疗效 Chemotherapy Phlebitis Hydropathie liquid Curative effect
作者简介 张齐放(1958-),女,副主任护师,本科,主要从事护理管理和护理教育。
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