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线粒体与阿尔茨海默病的研究进展 被引量:7

New insights into mitochondria and Alzheimer's disease
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摘要 阿尔茨海默病(Alzheimer’s disease,AD)是一种主要在老年期发生的以进行性痴呆为主要特征的神经元退行性疾病.其主要临床表现为进行性认知功能障碍、记忆力衰退、性格和行为改变等。病理学上以细胞外老年斑(SPs)形成及神经细胞内神经原纤维缠结(NFTs)为主要特衙。导致AD的原发因素目前尚不明确,其发病机制十分复杂。
作者 崔玉环 张朝东 魏玉磊 CUI Yu-huan, ZHANG Chao-dong, Wei Yu-lei. (Department of Neurology, First Affiliated Hospital of China Medical University, Shen yang 110001, China)
出处 《中华神经医学杂志》 CAS CSCD 北大核心 2010年第1期89-92,共4页 Chinese Journal of Neuromedicine
关键词 线粒体 阿尔茨海默病 Mitochondria Alzheimer' s disease
作者简介 通信作者:张朝东,Email:zhangchaodong@163.com
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