Objective To evaluate endovascular embolization with Onyx in treating brain arteriovenous malformations （AVM） located in the centre-encephalic region. Methods Eighteen patients with AVM in the brain centre-encephalic region were treated with embolization by using Onyx. According to Drake criteria of the AVM type, small type was seen in 10, medium type in 6 and large type in 2 cases. By using Onyx as embolization material, a total of 24 endovascnlar procedures were carried out. Results After treatment, complete obliteration was obtained in 12 cases （66.7%）, disability （symptoms worsened） resulted in 2 cases （11.2%） and no death occurred. In the medium type group and the small type group complete obliteration was seen in 3 （50%） and 9 （90%） cases respectively, the difference between the two groups was significant （P 〈 0.05）. Significant difference in complete obliteration rate existed between the patients with the feeding artery length 〉 2 cm and the patients with the feeding artery 〈 2 cm. Conclusion Embolization with Onyx is a safe and effective treatment for AVM located in the brain centre-encephalic region. Both the size of the abnormal vascular plexus and the length of the feeding artery carry a certain correlation with the complete obliteration rate.
Journal of Interventional Radiology
brain centre-encephalic region