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Onyx栓塞治疗脑中央区动静脉畸形 预览 被引量:12

Endovascular embolization with Onyx for the treatment of brain arteriovenous malformations located in the centre-encephalic region
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摘要 目的探讨Onyx胶栓塞治疗脑中央区动静脉畸形的效果。方法选择18例脑中央区动静脉畸形患者,按Drake标准分为小型10例、中型6例、大型2例,应用Onyx胶共行24次血管内栓塞治疗。结果经治疗后,完全栓塞12例(66.7%),致残(症状较术前加重)2例(11.1%),其中中型组完全栓塞3例(50%),与小型组完全栓塞9例(90%)比较差异有统计学意义(P〈0.05),无死亡病例。供血动脉长度大于2cm与小于2cm完全栓塞比较差异有统计学意义(P〈0.05)。结论Onyx胶栓塞治疗脑中央区动静脉畸形安全有效,畸形团大小和供血动脉长度对完全栓塞率有一定影响。 Objective To evaluate endovascular embolization with Onyx in treating brain arteriovenous malformations (AVM) located in the centre-encephalic region. Methods Eighteen patients with AVM in the brain centre-encephalic region were treated with embolization by using Onyx. According to Drake criteria of the AVM type, small type was seen in 10, medium type in 6 and large type in 2 cases. By using Onyx as embolization material, a total of 24 endovascnlar procedures were carried out. Results After treatment, complete obliteration was obtained in 12 cases (66.7%), disability (symptoms worsened) resulted in 2 cases (11.2%) and no death occurred. In the medium type group and the small type group complete obliteration was seen in 3 (50%) and 9 (90%) cases respectively, the difference between the two groups was significant (P 〈 0.05). Significant difference in complete obliteration rate existed between the patients with the feeding artery length 〉 2 cm and the patients with the feeding artery 〈 2 cm. Conclusion Embolization with Onyx is a safe and effective treatment for AVM located in the brain centre-encephalic region. Both the size of the abnormal vascular plexus and the length of the feeding artery carry a certain correlation with the complete obliteration rate.
作者 晁迎九 傅先明 张扬 魏建军 CHA O Ying-jiu, FU Xian-ming, ZHANG Yang, WEI Jian-jun. (Department of Neurosurgery, the Anhui Provincial Hospital Affiliated to Anhui Medical University, Hefei 230001, China)
出处 《介入放射学杂志》 CSCD 北大核心 2010年第1期 3-5,共3页 Journal of Interventional Radiology
关键词 动静脉畸形 脑中央区 栓塞治疗 ONYX胶 arteriovenous malformation brain centre-encephalic region embolization therapy Onyx
作者简介 通信作者:傅先明
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