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异位妊娠药物保守治疗的疗效分析

Efficacy of the conservative treatment for ectopic pregnancy
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摘要 目的探讨异位妊娠药物保守治疗的临床疗效。方法回顾性研究2005年8月至2010年2月期间确诊为异位妊娠并在我院住院进行药物保守治疗的114例患者,随机分为两组:A组66例用甲氨蝶呤(MTX)进行治疗,B组48例应用MTX联合米非司酮进行治疗,两组均辅以中药治疗,对比观察其临床疗效及不良反应。结果 A组总治愈率为71.2%,B组为81.3%,两组比较差异无统计学意义(P〉0.05)。A组第1个疗程治愈率为59.1%,B组为77.1%,两组比较差异有统计学意义(P〈0.05)。两组的不良反应发生率分别是25.8%及29.2%,两组比较差异无统计学意义(P〉0.05)。结论 MTX联合米非司酮治疗异位妊娠效果确切、剂量小、疗程短,是一种较理想的治疗方法。 Objective Discuss the clinical effect of ectopic pregnancy with the conservative treatment. Methods Retrospective studied 114 patients who had been diagnosed as ectopic pregnancy and treated in our hospital from August 2005 to February 2010.Diveded them into two groups.Group A treated with methotrexate,and group B treated with methotrexate and mifepristone.The two groups both treated with Chinese herbs.Compare both the clinical effect and the side reactions.Results The general cure rate : group A was 71.2% and group B was 81.3%.There was no statistical significance between them.The cure rate of the first periods: group A was 59.1% and group B was 77.1%.There was statistical significance between them.The side reactions: group A was 25.8% and group B was 29.2%.There was no statistical significance between them.Conclusion Treated ectopic pregnancy with methotrexate and mifepristone is effective and with low dose.It has short period.It is a good method.
作者 曹正珺 周琼青 杜洪灵 CAO Zhengjun,ZHOU Qiongqing,DU Hongling.People's Hospital of Putuo District,Shanghai 200060,China
出处 《临床医学》 CAS 2010年第9期 18-20,共3页 Clinical Medicine
关键词 异位妊娠 保守治疗 甲氨蝶呤 米非司酮 中药治疗 Conservative pregnancy Expectant treatment Methotrexate Mifepristone Treatment by Chinese herbs
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