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社区甲型流感临床特征分析与比较 被引量:2

Clinical features of 2009 pandemic influenza A (H1N1) in community:a comparative study
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摘要 目的分析和比较社区散发新型甲型H1N1流感和季节性流感临床特征,为临床诊治甲型流感提供参考依据。方法回顾性分析2009年5—10月来医院发热门诊就诊的具有流感样症状的患者,均经实时荧光定量PCR检测。结果在确诊的129例甲型流感患者中,新型甲型H1N1流感65例,占50.4%,季节性甲型流感64例,占49.6%;新型甲型H1N1流感组平均年龄21岁,季节性甲型流感组36岁,两组差异有统计学意义(P〈0.01);新型甲型HINl流感组学生占47例,占72.3%,季节性甲型流感组13例,占20.3%,两组差异有统计学意义(P〈0.01);从临床表现比较,除流涕、扁桃体肿大,两组差异有统计学意义(均P〈0.01)外;其他差异均无统计学意义。结论医院确诊的甲型流感患者均为轻型;新型甲型H1N1流感以年轻学生为主;两组甲型流感临床特征相似,需经PCR检测确诊分型。 OBJECTIVE To analyze clinical features of 2009 pandemic influenza A(HIN1) and seasonal influenza A. METHODS During May and Oct 2009, a total of 129 patients infected with influenza A who were quarantined in fever department of Jishultan Hospital were observed. Real-time-fluorescence quantitative polymerase-chain- reaction(PCR) assay was used to confirm infection. The clinical features of the disease were closely monitored. RESULTS The 129 patients infected with influenza A had 65 patients infected with 2009 pandemic influenza A (H1N1) and 64 patients infected with seasonal influenza A. The mean age of 2009 pandemic influenza A(H1N1) and influenza A were 21 years and 36 years, respectively. Students both influenza A were 47 and 13 ,respectively. Statistically significant difference was found (P〈0.01). Expect for rhinorrhea and swelling of tonsils,the clinical features of both influenza A had few statistica differences. CONCLUSIONS The patients investigated the influenza A in our hospital has a mild illness. The young students of 2009 pandemic influenza A(H1N1) are the major. The clinical features of both influenza A resemble. They need to be confirmed by PCR.
作者 李真 江倔 孙成栋 陈亮 冯丽 LI Zhen, JIANG Jue, SUN Cheng-dong, CHEN Liang, FENG Li (Bei Jishuitan Hospital, Beijing 100035, China)
出处 《中华医院感染学杂志》 CAS CSCD 北大核心 2011年第5期867-869,共3页 Chinese Journal of Nosocomiology
关键词 新型甲型H1N1流感 季节性流感 社区 临床特征 2009 pandemic influenza A (H1N1) Seasonal influenza A Community Clinical features
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