期刊文献+

丹夏乳癖片的提取工艺优选

Optimization of Extraction Process for Danxia Rupi Tablet
收藏 分享 导出
摘要 目的:优选丹夏乳癖片的提取工艺。方法:醇提部分以丹参酮ⅡA为评价指标,选择提取时间进行单因素考察。醇提后剩余药渣与其余药材合并进行水提,以丹参素为指标,采用L9(34)正交试验考察提取时间、溶媒用量、提取次数的影响,确定丹夏乳癖片的提取工艺。结果:最佳提取工艺为用95%乙醇10倍量提取1次,2 h;水提部分用10倍量水提取3次,每次2 h。结论:优选出的提取工艺简单、可行,适应药厂生产需要,可作为该制剂合理开发的依据。 Objective:To optimize optimum extraction technology of Danxia Rupi tablet.Method: Tanshinone ⅡA was used as index for alcohol extraction part,extraction time was selected for single factor test.Residue after ethanol extracting and other herbs were extracted by water together,L9(34) orthogonal experiment was used to determine extraction technology of Danxia Rupi tablet with danshensu as index,extraction time,the amount of solvent and extraction times were investigated as main factors affecting water boiling.Result: Optimum extraction process was:for alcohol extraction part,extracted 1 time with 10 times the amount of 95 % ethanol for 2 h.Water extraction part extracted 3 times with 10 times the amount of water for 2 hours each time.Conclution: This optimum technology was simple,feasible and adapt to industrial production,which could provide references for further investigation of Danxia Rupi tablet.
作者 张海鸣 刘子沐 方睿 王永炎 杜树山 ZHANG Hai-ming,LIU Zi-mu,FANG Rui,WANG Yong-yan,DU Shu-shan(Protection and Utilization of Traditional Chinese Medicine of Beijing Area Major Laboratory, Beijing Normal University,Beijing 100875,China)
出处 《中国实验方剂学杂志》 CAS 北大核心 2012年第5期 9-11,共3页 China Journal of Experimental Traditional Medical Formulae
基金 北京教育委员会共建项目(SYS100270430) 北京市新医药学科群重点支持项目(xk100270569)
关键词 丹夏乳癖片 提取工艺 单因素试验 正交试验 Danxia Rupi tablet extraction process single factor test orthogonal test
作者简介 张海鸣,博士研究生,从事中药物质基础研究,Tel:010-62208032,E-mail:zhanghaiming@mail.bnu.edu.cn [通讯作者]杜树山,博士,副教授,从事中药及其民族药物质基础研究,Tel:010-62208032,E.mail:dushushan@bnu.edu.cn
  • 相关文献

参考文献9

二级参考文献153

共引文献1216

投稿分析

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部 意见反馈