期刊文献+

托瑞米芬治疗乳腺疾病的临床研究进展 预览 被引量:9

在线阅读 下载PDF
收藏 分享 导出
摘要 他莫昔芬(tamoxifen)是一种选择性雌激素受体调节剂(selective estrogen receptor modulators SERMs),1977年在美国被批准用于雌激素阳性的乳腺癌患者。临床研究显示,对激素受体阳性的乳腺癌患者使用他莫昔芬辅助治疗5年能显著提高患者的DFS和总生存率。
作者 王明浩 姜军
出处 《中华乳腺病杂志(电子版)》 CAS 2013年第2期51-55,共5页 Chinese Journal of Breast Disease (Electronic Version)
作者简介 通信作者:姜军,Email:jcbd@medmail.com.cn
  • 相关文献

参考文献39

  • 1Early Breast Cancer Trialists' Collaborative Group (EBCTCG). Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials [J]. Lancet, 2005,365 (9472) : 1687 -1717. 被引量:1
  • 2Osborne CK. Tamoxifen in the treatment of breast cancer [J]. N Engl J Med, 1998,339(22) :1609-1618. 被引量:1
  • 3Pyrhonen S, Ellmen J, Vuorinen J, et al.Meta-analysis of trials comparing toremifene with tamoxifen and factors predicting outcome of anti estrogen therapy in postmenopausal women with breast cancer [J]. Breast Cancer Res Treat, 1999, 56 ( 2 ) : 133-143. 被引量:1
  • 4Zhou WB, Ding Q, Chen L, et al.Toremifene is an effective and safe alternative to tamoxifen in adjuvant endocrine therapy for breast cancer: results of four randomized trials [J]. Breast Cancer Res Treat, 2011 ,128 ( 3 ) : 625 -631. 被引量:1
  • 5Gennari L, Merlotti D, Stolakis K, et al.Pharmacokinetic evaluation of toremifene and its clinical implications for the treatment of osteoporosis [J]. Expert Opin Drug Metab Toxicol, 2012,8(4) :505-513. 被引量:1
  • 6Lewis JD, Chagpar AB, Shaughnessy EA, et al.Excellent outcomes with adjuvant toremifene or tamoxifen in early stage breast cancer[J]. Cancer, 2010,116(10): 2307-2315. 被引量:1
  • 7Kusama M, Miyauchi K, Aoyama H, et al.Effects of toremifene ( TO R) and tamoxifen (TAM) on serum lipids inpost menopausal patients with breast cancer [J]. Breast Cancer Res Treat, 2004,88(1) :1-8. 被引量:1
  • 8Warri AM, Huovinen RL, Laine AM, et al.Apoptosis in toremifene-induced growth inhibition of human breast cancer cells in vivo and in vitro[J]. J Natl Cancer Inst , 1993,85 (17) : 1412-1418. 被引量:1
  • 9Gershanovich M, Garin A, Baltina D, et al.A phase ill comparison of two toremifene doses to tamoxifen in postmenopausal women with advanced breast cancer. Eastern European Study Group [J]. Breast Cancer Res Treat, 1997 , 45 ( 3) : 251-262. 被引量:1
  • 10Hirsirnaki P, Aaltonen A. Toxicity of antiestrogens [J]. Breast J,2002,8 (2) :92-96. 被引量:1

同被引文献121

引证文献9

二级引证文献42

投稿分析

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部 意见反馈