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某院2011-2012年门诊患者超说明书用药分析 被引量:4

Analysis of Off-label Drug Use in Outpatients of a Hospital during 2011--2012
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摘要 目的:调查某院超说明书用药现状,分析其原因及合理性,并提出相应的解决对策。方法:回顾性随机抽取该院2011-2012年门诊患者的处方,依据药品说明书,判断其是否超说明书用药,并进行分析。结果与结论:共抽取门诊处方3 826张,超说明书用药的处方有182张,发生率为4.76%。该院门诊患者总体来说超说明书用药情况较少见,但儿科患者超说明书用药情况普遍。在临床治疗过程中,因特殊医疗需要,超说明书用药偶有存在,临床医师应严格掌握超说明书用药的适用范围,借鉴国内外经验,确保临床用药安全、有效、经济、合理。 OBJECTIVE: To investigate the status quo of off-label drug use in a hospital, and to analyze the causes and ratio- nality of off-label drug use and put forward relevant solutions. METHODS: The prescriptions of outpatients were randomly selected from the hospital during 2011- 2012 retrospect ively. The off-label drug use of them was confirmed and analyzed by package in- serts. RESULTS & CONCLUSIONS: A total of 3 826 outpatient prescriptions were selected and 182 of them were off-label drug use, accounting for 4.76%. Generally speaking, the off-label drug use in outpatients is at rare level in the hospital, but the pediat- ric patients are more common in off-label drug use. There is the off-label drug use occasionally during the clinic treatment due to the special demands; however, the clinic physicians shall strictly control the application of the off-label drug use by referring to the experience at home and abroad to ensure safe, effective, economical and appropriate use of drugs in the clinic.
作者 谭谡 TAN Su(Armed Police Chongqing Corps Hospital, Chongqing 400061, China)
出处 《中国药房》 CAS CSCD 2013年第38期3574-3577,共4页 China Pharmacy
关键词 超说明书用药 门诊用药 合理用药 用药安全 Off-label drug use Outpatient drug use Rational drug use Safety of drug use
作者简介 硕士。研究方向:临床药学。电话:023—62523015。E—mail:poiooo@163.com
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