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低剂量秋水仙碱联合双氯芬酸钠治疗痛风急性发作疗效观察 被引量:6

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摘要 目的:探讨低剂量秋水仙碱联合双氯芬酸钠治疗痛风急性发作的临床疗效与不良反应。方法:痛风急性发作患者70例随机分为治疗组和对照组各35例,对照组首次服用秋水仙碱片1.0 mg,以后每2 h服用0.5mg;治疗组服用秋水仙碱片0.5 mg,tid,双氯芬酸钠肠溶片25 mg,tid。比较两组患者用药后疼痛缓解率和缓解时间、临床疗效及不良反应发生率。结果:治疗组总有效率94.3%,对照组总有效率91.4%,两组患者用药后疼痛缓解率和缓解时间、总有效率等比较,差异无统计学意义(P〉0.05);不良反应发生率治疗组为11.4%,对照组为68.6%,差异有统计学意义(P〈0.05)。结论:低剂量秋水仙碱联合双氯芬酸钠治疗痛风急性发作疗效好,不良反应少,安全性高。
出处 《药物流行病学杂志》 CAS 2013年第9期469-470,共2页 Chinese Journal of Pharmacoepidemiology
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