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江苏省2012年健康人群麻疹-风疹-腮腺炎IgG抗体水平监测分析 被引量:26

Analysis of measles, rubella and mumps antibody level in healthy people in Jiangsu province in 2012
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摘要 目的了解和掌握江苏省不同年龄组健康人群的麻疹、风疹、腮腺炎免疫现状,对其抗体水平进行监测,并结合当年麻疹、风疹、腮腺炎发病率,为麻疹、风疹、腮腺炎控制提供依据。方法选择江苏省3个市健康人群,按年龄分为0月龄-7月龄,8月龄-17月龄,1.5岁~2岁,3岁~4岁,5岁~6岁,7岁~9岁,10岁-14岁,15岁~19岁,20岁以上,流动人口20岁以上,共10个年龄段。使用酶联免疫吸附试验(ELISA)检测麻疹、风疹、腮腺炎IgG抗体并计算其抗体阳性率、几何平均浓度(Geometric Mean Concentration,GMC)。结果检测标本1502例,每例完成麻疹、风疹、腮腺炎IgG三个项目的检测,各年龄组之间麻疹、风疹、腮腺炎抗体阳性率差异有统计学意义。各年龄组之间麻疹、风疹、腮腺炎抗体GMC差异有统计学意义。结论江苏省健康人群的麻疹、风疹抗体阳性率较高,发生大范围的暴发或流行的风险较低,但个别地区的个别年龄组阳性率较低,需加强免疫;腮腺炎抗体阳性率较低,在个别年龄组需要加强免疫,或调整现有免疫策略。 Objective To understand and master the immunization status of measles, rubella and mumps in healthy population at different age in Jiangsu province, to monitor the antibody level, so as to provide basis for prevention and control of measles, rubella and mumps. Methods Normal people in 3 cities of Jiangsu province were divided into 10 age groups (0 - 7 months old, 8 -17 months old, 1.5 -2 years old, 3 -4 years old, 5 -6 years old, 7 -9 years old, 10 - 14 years old, 15 - 19 years old, more than 20 years old, floating population more than 20 years old), and the IgG antibody of measles, rubella, mumps were detected using ELISA, then the positive rates and geometric mean concentration (GMC) of antibody were calculated. Results The specimens of 1502 cases were detected for measles, rubella and mumps. There was no statistical significance difference in positive rate and GMC of measles, rubella, mumps antibody among different age groups. Conclusion The positive rates of measles and rubella antibody in healthy population were higher in Jiangsu province, less risk for outbreak or epidemic in large range, but low positive rate was still found in several age groups, need to strengthen the immune. The positive rate of mumps antibodies was slightly low, so individual age group need to strengthen the immunity or change existing immunization strategy.
作者 胡莹 陆培善 邓秀英 刘元宝 冷红英 吴昀 HU Ying, LU Pei -shan, DENG Xiu- ying, LIU Yuan -bao, LENG Hong- ying, WU Yun Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China
出处 《中国卫生检验杂志》 北大核心 2013年第12期2650-2654,共5页 Chinses Journal of Health Laboratory Technology
关键词 麻疹 风疹 腮腺炎 抗体水平 Measles Rubella Mumps Antibody level
作者简介 胡莹(1979-),女,硕士,主管技师,主要从事计划免疫相关疾病的病原微生物检测方面研究。
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