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江苏省2010年-2011年流行性乙型脑炎流行特点及健康人群病毒抗体水平分析 被引量:11

Analysis of epidemic characteristics and viral antibody level among healthy people against Japanese encephalitis in Jiangsu province during 2010 - 2011
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摘要 目的了解江苏省2010年-2011年流行性乙型脑炎流行特点及健康人群病毒抗体水平。方法采用描述流行病学方法对2010年-2011年江苏省监测的70例乙脑病例进行分析。健康人群乙脑抗体水平的测定采用蚀斑减少中和实验,选择〈1岁、1岁-2岁、3岁~4岁、5岁-6岁、7岁~14岁、15岁~19岁、920岁共7个年龄组健康人群作为调查对象,共1410人。结果2010年和2011年江苏省乙脑年发病率分别为0.0712/10万、0.0191/10万,其中2010年死亡率为0.0039/10万。7月-9月为流行高峰。发病主要集中在7岁以下儿童。乙脑抗体总的阳性率为65.11%,几何平均滴度(GMT)为1:11.64。结论江苏省乙脑发病率维持在较低水平,发病呈明显的季节性、地域性。15岁以上人群乙脑抗体水平具有保护作用。乙脑低滴度抗体水平主要集中在小年龄组,应加强儿童免疫监测。 Objective To understand the epidemic characteristics and viral antibody level among healthy people of Japanese en- cephalitis in Jiangsu province during 2010 - 2011. Methods A total of 70 Japanese encephalitis cases were investigated using descriptive epidemiological method in Jiangsu province during 2010 -2011. One thousand, four hundred and ten healthy people were selected and divided into seven age groups : less than one year old, 1 - 2 years old, 3 - 4 years old, 5 - 6 years old, 7 - 14 years old, 15 - 19 years old and above 20 years old, and Japanese encephalitis viral antibody was detected by plaque reduc- tion neutralization. Results The incidence rates of Japanese encephalitis were 0. 0712/100,000 and 0. 0191/100 , 000 respec- tively in 2010 and 2011 in Jiangsu province, the mortality rate was 0. 0039/100,000 in 2010. July, August and September were the epidemic peak periods. The cases concentrated on children under 7 years old. The total positive rate of Japanese encephalitis viral antibody was 65.11%, and GMT was 1 : 11.64. Cortelusion Japanese encephalitis incidence rate remains at a low level in Jiangsu province, and the incidence shows seasonal and regional characteristics. The Japanese encephalitis antibody can exert a protective effect on persons over 15 years old. The younger children with lower Japanese encephalitis antibody level should be strengthened the immune monitoring.
作者 邓秀英 高君 陆培善 胡莹 马福宝 DENG Xiu-ying, GAO Jun, LU Pei- shaM, HU Ying, MA Fu-bao Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China
出处 《中国卫生检验杂志》 北大核心 2014年第4期576-579,共4页 Chinses Journal of Health Laboratory Technology
关键词 流行性乙型脑炎 流行病学 抗体水平 血清学监测 Japanese encephalitis Epidemiology Antibody level Serological monitoring
作者简介 邓秀英(1983-),女,硕士在读,技师,主要从事计划免疫相关疾病的实验室检测工作。
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