期刊文献+

慢性鼻-鼻窦炎内镜手术应用布地奈德混悬液中鼻道浸润的长期疗效观察 被引量:7

Long-term outcome of budesonide middle meatus treatment for chronic rhinosinusitis patients following endoscopic sinus surgery
收藏 分享 导出
摘要 目的:探讨慢性鼻-鼻窦炎内镜手术应用布地奈德混悬液中鼻道浸润的长期疗效。方法:将53例慢性鼻-鼻窦炎患者分为布地奈德组和对照组,其中布地奈德组21例(39.6%),对照组32例(60.4%)。布地奈德组于鼻内镜鼻窦手术完成时每侧中鼻道放置1ml吸入用布地奈德混悬液浸润的明胶海绵,对照组中鼻道只放置明胶海绵。术前及术后24个月分别对患者进行视觉模拟量表(VAS)、鼻窦炎生活质量量表(SNOT-20)及LundKennedy内镜评分。结果:布地奈德组VAS及SNOT-20评分术前与术后比较,差异均有统计学意义(P〈0.05);Lund-Kennedy内镜评分术前与术后比较,差异均有统计学意义(P〈0.05)。对照组VAS及SNOT-20评分术前与术后比较,差异均有统计学意义(P〈0.05);Lund-Kennedy内镜评分术前与术后比较,差异均有统计学意义(P〈0.05)。2组总体症状VAS评分术前与术后比较,差异均有统计学意义(P〈0.05);但2组术前与术后SNOT-20评分与2组术前与术后Lund-Kennedy内镜评分比较,差异均无统计学意义(P〉0.05)。结论:慢性鼻-鼻窦炎经鼻内镜鼻窦手术应用布地奈德混悬液中鼻道浸润,是一种安全、便捷、有效的方法,可改善患者手术后鼻部症状。 Objective:To investigate the long term clinical effect of budesonide treatment in middle meatus for chronic rhinosinusitis(CRS)following endoscopic sinus surgery(ESS).Method:A total number of 53 patients with CRS received ESS were divided into two groups according to budesonide treatment:budesonide-treated group with 21 cases(39.6%)and control group with 32 cases(60.4%).Gelatin sponges soaked with 1ml budesonide suspension were put in middle meatus in budesonide-treated group,while only gelatin sponges were put in middle meatus in control group.Visual analogy score(VAS),sino-nasal outcome test-22(SNOT-22)and Lund-Kennedy endoscopic scale were carried out before ESS and two years after ESS.Result:In budesonide-treated group,there were a statistical difference before and after ESS in the VAS,SNOT-20 and Lund-Kennedy score(P〈0.05).In control group,difference was also significant in VAS,SNOT-20 and Lund-Kennedy score before and after ESS(P〈0.05).The VAS gap of post-operative and pre-operative in two groups are significantly different(P〈0.05).However,there was no significant difference in the SNOT-20 and Lund-Kennedy endoscopic scale gap before or after the operation between two groups.Conclusion:It is safe,convenient and practicable to perform budesonide treatment in middle meatus following ESS,which can significantly ease the post-operative discomfort of nose.
作者 陈晓栋 王海婷 石照辉 李晓媛 单伯仪 薛涛 乔莉 陈福权 CHEN Xiaodong,WANG Haiting,SHI Zhaohui,LI Xiaoyuan,SHAN Boyi,XUE Tao,QIAO Li,CHEN Fuquan(Department of Otorhinolaryngology Head and Medical University, Xi'an, 710032, China) Neck Surgery, Xijing Hospital, Fourth Military
出处 《临床耳鼻咽喉头颈外科杂志》 CAS 北大核心 2016年第3期203-205,208共4页 Journal of Clinical Otorhinolaryngology
关键词 鼻窦炎 内镜鼻窦手术 糖皮质激素类 布地奈德 sinusitis endoscopic sinus surgery glucocorticoids budesonide
作者简介 通信作者:陈福权,E—mail:chenfq@fmmu.edu.cn
  • 相关文献

参考文献18

二级参考文献82

  • 1PRANSKY S M, LOW W S. Pediatric ethmoidectomy[J]. Otolaryngol Clin North Am, 1996 , 29: 131 --142. 被引量:1
  • 2[4]Emanuel IA,Shah SB.Chronic rhinosinusitis:allergy and sinus computed tomography relationship.Otolaryngol Head Neck Surg,2000;123:687~691 被引量:1
  • 3[5]Delank KW,Srol W.lfactory function after functional endoscopic sinus surgery for chronic sinusitis.Rhinology,1998;36:15~19 被引量:1
  • 4[7]Dhong Hj,Jung YS,Chung SK,et al.Effect of endoscopic sinus surgery on asthmatic patients with chronic rhinosinusitis.Otolaryngol Head Neck Surg,2001;124:99~104 被引量:1
  • 5中华医学会耳鼻咽喉科学分会,中华耳鼻咽喉科杂志编辑委员会.慢性鼻窦炎鼻息肉临床分型分期及内窥镜鼻窦手术疗效评定标准(1997 年,海口),1998, 33(3): 134. 被引量:1
  • 6Fokkens WJ, Lund VJ, Mullol J, et al. European Position Paperon Rhinosinusitis and Nasal Polyps 2012. Rhinol Suppl’ 2012(23) : 1-298. 被引量:1
  • 7Lund VJ, Mackay IS. Staging in rhinosinusitus. Rhinology,1993,31(4) : 183-184. 被引量:1
  • 8Lund VJ, Kennedy DW. Staging for rhinosinusitis. OtolaryngolHead Neck Surg,1997,117 (3 Pt 2) ; S3540. 被引量:1
  • 9乔莉,查定军,张旭,薛涛,孟美娟.普米克令舒在儿童慢性鼻窦炎治疗中的作用[J].临床耳鼻咽喉头颈外科杂志,2007,21(20):942-943. 被引量:1
  • 10韩德民,许庚.FESS-95广州标准(慢性鼻窦炎、鼻息肉临床分型及内窥镜鼻窦手术疗效评定标准)[J].临床耳鼻咽喉科杂志,1997,11(1):46-46. 被引量:74

共引文献561

同被引文献51

二级引证文献8

投稿分析

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部 意见反馈