期刊文献+

中国首例输入性寨卡病毒病患者的中西医结合治疗经验 被引量:7

Experience of integrated traditional Chinese and Western medicine in first case of imported Zika virus disease in China
收藏 分享 导出
摘要 目的寨卡病毒病是由寨卡病毒通过伊蚊叮咬传播的急性传染病。报告中国首例输入性寨卡病毒病患者的诊治经过,探讨中西医结合的治疗作用。方法江西省赣县人民医院于2016年2月6日收治了中国首例输入性寨卡病毒病患者,经过9d的隔离治疗痊愈出院。介绍临床诊治过程,分析中药喜炎平注射液的抗病毒作用。结果患者男性,34岁,因“发热9d,眼眶痛、皮疹伴瘙痒4d”于2016年2月6日入院。①流行病学特征:1月1日患者前往委内瑞拉出差,期间常被蚊虫叮咬,当地正在流行寨卡病毒病。委内瑞拉当地时间1月20日患者曾出现头晕,无发热,自行购药(具体不详)服用后症状消失;1月28日稍感头晕、畏寒、低热,呈阵发性发作,无肌肉酸痛;2月3日颈部出现散在细小红色皮疹,随后蔓延到前胸、四肢、躯干,仍有低热、乏力、恶心,耳后、眼眶开始出现阵发性针刺样疼痛,期间一直未治疗;2月4日上述症状逐渐好转减轻。北京时间2月5日患者回到赣县后解黄色稀便3次,体温正常,颈部仍有散在皮疹,无腹痛;2月6日在赣县人民医院诊治。②临床表现:入院体温36.8℃,脉搏80次/min,呼吸频率20次/rain,血压110/70mmHg(1mmHg=0.133kPa),颈前区有散在淡红色细小皮疹,全身浅表淋巴结无肿大,双侧眼结膜充血明显,生理反射存在,病理反射未引出。⑧辅助检查:2月6日查血常规正常,活化部分凝血活酶时间(Ar,'rr)轻度延长(38.6s),肝肾功能、心肌酶谱、电解质、血糖、C-反应蛋白(CRP)、肌钙蛋白I(TnI)、降钙素原(PCT)均正常。2月8日胸部CT示左肺絮状阴影,结合发热病史,考虑炎性变和轻度肺气肿改变(左下肺为主);双肾结石。心电图及肝、脾、胰B超均未见明显异常。④病毒检测确诊过程:2月6日赣州市疾病控制中心(CDC)� Objective Zika virus disease is an acute infectious disease caused by Zika virus transmitted through Aedes mosquitoes. To explore the therapeutic effect of integrated traditional Chinese and Western Medicine for Zika virus disease, the treatment process of the first imported case in China was reviewed. Methods The first imported Zika virus disease in China was admitted to Ganxian People's Hospital in Jiangxi Province on February 6th, 2016, and the patient received isolation treatment for 9 days and cured later. The effect of antiviral treatments including Xiyanping injection was evaluated based on clinical diagnosis and treatment process of the patient. Results A 34-year old male patient was admitted with chief complaint of fever for 9 days, orbital pain and itching rash for 4 days on February 6th, 2016. (!) Epidemiological characteristics: the patient was bitted by mosquitoes during his business trip in Venezuela since January 1st, where Zika virus disease was ~preading. On January 20th he had dizziness without fever, and the symptom disappeared after taking medicines without details. Paroxysmal dizziness, chills and mild fever without myalgia was experienced on January 28th. On February 3rd small red rash appeared in the neck, spreading to anterior part of chest, limbs and trunk, and the fever, fatigue, nausea was continued, and a new symptom of paroxysmal pain in back of ears and orbits appeared, during which he had not go to hospital. The symptoms relieved on February 4th. He returned to Ganxian County on February 5th, he had yellow stool 3 times with normal temperature, without abdominal pain, and red rash still appeared in the neck. He went to Ganxian People's Hospital on February 6th, 2016. (1) Clinical manifestation: the vital signs showed a temperature of 36.8 ℃ , a pulse rate of 80 bpm, a respiratory rate of 20 bpm, and a blood pressure of 110/70 mmHg (1mmHg = 0.133 kPa). It was showed by physical examination that red rash appeared in the neck, and no superficial enlarged lymph nod
作者 邓宜楚 曾莉萍 包文 徐平华 钟功荣 Deng Yichu, Zeng Liping, Bao Wen, Xu Pinghua, Zhong Gongrong( Department of Infectious Disease, Ganxian People's Hospital, Ganxian 341100, Jiangxi, China)
出处 《中华危重病急救医学》 CAS CSCD 北大核心 2016年第2期106-109,共4页 Chinese Critical Care Medicine
关键词 寨卡病毒病 喜炎平注射液 中西医结合治疗 Zika virus Treatment of traditional Chinese medicine and Western medicine Xiyanpinginjection
作者简介 通讯作者:钟功荣,Email:zgr1965@sina.com
  • 相关文献

参考文献18

  • 1Ioos S, Mallet HP, Leparc GI, et al. Current Zika virus epidemiology and recent epidemics [J]. Med Mal Infect, 2014, 44 (7): 302-307. DOh 10.1016/j.medmal.2014.04.008. 被引量:1
  • 2Bierlaire D, Beau F, Lastere S, et al. Virus ZIKA en Polyn6sie francaise: h6movigilance receveur [J]. Transfus Clin Biol, 2014, 21 (4-5): 234. DOI: 10.1016/j.tracli.2014.08.005. 被引量:1
  • 3Nhana TX, Cao-Lormeaub VM, Mussoa D, et al. Les infections vires Zika [J]. RFL, 2014, 2014 (467): 45-52. DOI: 10.1016/ S1773-035X(14)72748-0. 被引量:1
  • 4国家卫生和计划生育委员会.寨卡病毒病诊疗方案(2016年第1版)[EB/OL].(2016—02—03).http://www.nhfpc.gov.cn/yzygj/s3593g/201602/e7c1402a03024501ad8f036de346c145.shtml. 被引量:2
  • 5毕连红.喜炎平注射液治疗老年带状疱疹108例疗效观察[J].当代医学,2009(16):130-131. 被引量:11
  • 6Bi LH. The curative effect of Xiyanpin injection in eider patients with herpes zoster: a observation of 108 cases [J]. Contemp Med, 2009, 15 (16): 130-131. DOI: lO.3969/j.issn.1009-4393.2009.16.099. 被引量:1
  • 7张霞,付强.穿心莲破坏内毒素作用的体外实验研究[J].中国中西医结合急救杂志,2000,7(4):212-214. 被引量:55
  • 8Zhang X,-Wu D, Wang JT, et al. Experimental study of the destructive effect of Xiyanping on endotoxin in vitro [J]. Chin J TCM WM Crit Care, 2000, 7 (4): 912-214. DOI: 10.3969/j.issn.1008-9691. 2000.04.007. 被引量:1
  • 9曲晓宇,周微,张四喜,张欣,陶娌娜,董雷.喜炎平注射液治疗小儿手足口病疗效的Meta分析[J].儿科药学杂志,2014,20(1):6-11. 被引量:18
  • 10Qu xY, Zhou W, Zhang SX, et al. The efficacy of Xiyanping injection in the treatment of hand-foot-mouth disease : a Meta- analysis [J]. J Pediatr Pharm, 2014, 20 (1): 6-11. 被引量:1

二级参考文献96

共引文献175

同被引文献136

  • 1膝贵明,苏忠鑫,罗力,于竟进,于明珠,苏海军,汪华,张瑜,刘岭,施培武,雷杰,陈政,吕军,陈英耀,郝模.市县2级疾病预防控制机构检验能力差异分析[J].中国公共卫生,2006,22(7):875-876. 被引量:8
  • 2Blazquez AB, Escribano-Romero E, Merino-Ramos T, et al.Stress responses in flavivirus-infected cells: activation ofunfolded protein response and autophagy[J], Front Microbiol.2014,3(5):266. 被引量:1
  • 3Ginier M, Neumayr A, Gunther S, et al. Zika withoutsymptoms in returning travellers: what are the implications[J], Travel Med Infect Dis,2016, 14(1) : 16-20. 被引量:1
  • 4Carteaux G, Maquart M,Bedet A,et al. Zika virus associatedwith meningoencephalitis [ J]. N Engl J Med, 2016 Mar 9.[Epub ahead of print]. 被引量:1
  • 5Mecharles S,Herrmann C, Poullain P,et al. Acute myelitisdue to Zika virus infection[J]. Lancet, 2016,pii: S0140-6736(16)00644-9. 被引量:1
  • 6Oehler E, Watrin L, Larre P,et al. Zika virus infectioncomplicated by Guillain-Barre syndrome-case report, FrenchPolynesia, December 2013 [J]. Euro Surveill, 2014, 19(9).pii: 20720. 被引量:1
  • 7Martines RB, Bhatnagar J, Keating MK, et al. Notes fromthe field: evidence of Zika virus infection in brain and placentaltissues from two congenitally infected newborns and two fetalLosses-Brazil, 2015 [J]. MMWR Morb Mortal Wkly Rep,2016, 65(6):159-160. 被引量:1
  • 8Rubin EJ,Greene MF, Baden LR. Zika virus andmicrocephaly[J]. N Engl J Med, 2016, Feb 10. [Epub aheadof print]. 被引量:1
  • 9Tang H, Hammack C, Ogden SC, et al. Zika virus infectshuman cortical neural progenitors and attenuates their growth[J]. Cell Stem Cell, 2016,Mar 3. [Epub ahead of print]. 被引量:1
  • 10Gulland A. Zika virus is a global public health emergency,declares WHO[J], BMJ, 2016,Feb 2. [Epub ahead of print]. 被引量:1

引证文献7

二级引证文献10

投稿分析

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部 意见反馈