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氯化钠注射液和甘油灌肠剂对复杂性肛瘘患者术后排便的影响 预览 被引量:3

Effects of Sodium Chloride Injection and Glycerine Enema on Postoperative Defecation in Patients with Com-plex Anal Fistula
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摘要 目的:观察氯化钠注射液和甘油灌肠剂对复杂性肛瘘患者术后排便疼痛的缓解程度,及其对创面和切口周围组织水肿的影响。方法:选取复杂性肛瘘住院患者100例,按照随机数字表法分为A组(33例)、B组(33例)和C组(34例)。A组患者给予氯化钠注射液300~500 ml,水浴加热至35~37℃,于排便前经灌肠袋快速注入直肠,控便5~10 min后排便;B组患者给予甘油灌肠剂110 ml注入直肠,控便5~10 min后排便;C组患者便意明显时直接排便。观察3组患者初次排便视觉模拟量表(VAS)评分、初次排便后24 h内的排便次数及排便时间、初次排便后1周内创面及切口周围组织水肿情况以及不良反应发生情况。结果:A组和B组患者初次排便VAS评分、排便次数、排便时间、创面及切口周围组织水肿情况均明显低/少于C组,差异均有统计学意义(P<0.05);B组患者上述指标略低于A组,但差异无统计学意义(P>0.05)。A组和B组患者治疗过程中均未见明显不良反应发生。结论:氯化钠注射液和甘油灌肠剂均对复杂性肛瘘患者术后排便疼痛有缓解作用,可减轻创面及切口周围组织水肿,安全性良好,临床可针对患者情况酌情选用。 OBJECTIVE:To observe the effects of Sodium chloride injection and Glycerine enema on the relief of postoperative defecation pain,edema around wound and incision in patients with complex anal fistula. METHODS:100 patients with complex anal fistula were selected and divided into group A(33 cases),B(33 cases)and C(34 cases)according to random number table. Group A was given Sodium chloride injection 300-500 ml,water bath heated to 35-37℃,into the rectum via enema bag before defecation,and defecated after controlling defecation for 5-10 min. Group B was given Glycerine enema 110 ml into the rectum,and defecated after controlling defecation for 5-10 min. Group C could defecated directly when they felt obvious defecation desire. VAS score of initial defe-cation,defecation frequence and time within 24 h after initial defecation,edema around wound and incision within a week after initial defecation were observed in 3 groups as well as the occurrence of ADR. RESULTS:VAS score of initial defecation,defecation fre-quence and time,edema around wound and incision in group A and B were significantly lower/shorter than in group C,with statistical significance(P〈0.05). Above indexes of group B were slightly lower than those of group A,without statistical significance(P〉0.05). No obvious ADR was found in group A and B during treatment. CONCLUSIONS:Both Sodium chloride injection and Glycerine enema can relieve postoperative defecation pain in patients with complex anal fistula,and reduce edema around wound and incision with good safety. The two drugs should be selected according to patient’s condition.
作者 王银光 陈加林 张搏 徐月 WANG Yinguang, CHEN Jialin, ZHANG Bo, XU Yue (Dept. ofAnorectal, Chongqing Hospital of TCM, Chongqing 400021, China)
出处 《中国药房》 CAS 北大核心 2016年第35期4950-4952,共3页 China Pharmacy
基金 重庆市中医院院内培育课题(No.2014-2-15)
关键词 复杂性肛瘘 氯化钠注射液 甘油灌肠剂 排便疼痛 水肿 灌肠 Complex anal fistula Sodium chloride injection Glycerine enema Defecation pain Edema Enema
作者简介 主治医师,硕士。研究方向:肛肠科。电话:023—67063952。E—mail:314629288@qq.com 通信作者:主任医师。研究方向:肛肠科。电话:023—67063952。E—mail:827093411@qq.com
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