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氯沙坦钾片联合肾炎康复片治疗慢性肾小球肾炎蛋白尿的疗效观察 预览 被引量:13

Observation on Efficacy of Losartan Potassium Tablets Combined with Shenyankangfu Tablets in Treatment of Proteinuria of Chronic Nephritis Proteinuria
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摘要 目的:探讨氯沙坦钾片联合肾炎康复片治疗慢性肾小球肾炎蛋白尿的疗效。方法:选取2014年5月—2016年1月潜江市中心医院收治的慢性肾小球肾炎蛋白尿患者68例作为研究对象。根据抽签法将患者随机分为观察组和对照组,每组各34例。对照组患者给予肾炎康复片治疗,观察组患者给予氯沙坦钾片联合肾炎康复片治疗。观察2组患者的疗效。结果:观察组患者的总有效率为94.12%(32/34),明显高于对照组的79.41%(27/34),差异有统计学意义(P〈0.05);观察组患者不良反应发生率为8.82%(3/34),明显低于对照组的17.65%(6/34),差异有统计学意义(P〈0.05)。结论:氯沙坦钾片联合肾炎康复片治疗慢性肾小球肾炎蛋白尿,疗效显著,不良反应少,安全性高。 OBJECTIVE: To probe into the efficacy of Losartan potassium tablets combined with Shenyankangfu tablets in treatment of proteinuria of chronic nephritis proteinuria. METHODS: 68 patients with proteinuria of chronic nephritis proteinuria admitted into Qianjiang Central Hospital from May 2014 to Jan. 2016 were selected to be divided into observation group and control group via the random drawing methods,with 34 cases in each. The control group were treated with Losartan potassium tablets,while the observation group were given Losartan potassium tablets combined with Shenyankangfu tablets. The efficacy of two groups were observed. RESULTS: The total effective rate of observation group was 94. 12%( 32 /34),significantly higher than that of control group [79. 41%( 27 /34) ],with statistically significant difference( P〈0. 05). The incidence of adverse drug reactions of observation group was 8. 82%( 3 /34),significantly higher than that of control group [17. 65%( 6 /34) ], with statistically significant difference( P〈0. 05).CONCLUSIONS: The efficacy of Losartan potassium tablets combined with Shenyankangfu tablets in treatment of proteinuria of chronic nephritis proteinuria is remarkable with few adverse drug reactions and high safety.
作者 李名波 孙智梅 任卓琴 董平定 LI Mingbo, SUN Zhimei, REN Zhuoqin, DONG Pingding ( Dept. of Nephrology, Qianjiang Central Hospital, Hubei Qianjiang 433100, China)
出处 《中国医院用药评价与分析》 2017年第1期75-76,共2页 Evaluation and Analysis of Drug-use in Hospitals of China
关键词 慢性肾小球肾炎蛋白尿 肾炎康复片 氯沙坦钾 疗效 不良反应 Proteinuria of Chronic nephritis proteinuria Shenyan kangfu tablets Losartan potassium Efficacy Adverse drug reaction
作者简介 副主任医师。研究方向:慢性肾衰竭。E-mail:827289934@qq.com
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