In recent 30 years, the incidence of multiple pregnancy has increased significantly, which has a great impact on maternal and infant outcomes. Multifetal pregnancy reduction （MFPR） is an ethically acceptable procedure aimed to avoid multiple births and improve pregnancy outcome. The clinical factors that affect the pregnancy outcome of MFPR mainly include the gestational age of reduction, the operation mode, the number of initial and final embryos and whether is multi-pregnancy accompany monochorionic twins. In addition, prenatal diagnosis has an accurate guidance for the selection of the object for MFPR. In this paper, the current status of MFPR and its related clinical factors influencing the outcome of pregnancy were reviewed.
Reproduction and Contraception