期刊文献+

人体测量学肥胖指标与微量白蛋白尿的相关性研究 被引量:2

Study on the correlation between anthropometric obesity index and microalbuminuria
收藏 分享 导出
摘要 目的 探讨人体测量学肥胖指标与微量白蛋白尿(microalbuminuria,MAU)的相关性.方法 在青岛市城阳区人民医院2012年流行病学调查数据库中收集调查人群1170例,留取清晨随机尿测定尿微量白蛋白(urinary albumin,UAlb)和尿肌酐(urinary creatine,UCr),计算比值(urinary albumin creatine rate,UACR)并根据UACR水平分为:正常白蛋白尿组(nornal albumin urine,NAU)(807例)和MAU组(363例),收集人体测量学指标和测定生化指标,作统计学处理.结果 ①与NAU组相比,MAU组年龄、空腹血糖(fasting blood glucose,FBG)、舒张压(diastolic blood pressure,DBP)、收缩压(systolic blood pressure,SBP)、血清尿酸(serun urinary acid,SUA)、腰围(waist circumference,WC)、腰身比(Waist to height ratio,WTHR)、腰臀比(Waist to hip ratio,WHR)均高于前者,差异有统计学意义(P<0.05或P<0.01);与NAU组相比,MAU 组高血糖(hyperglycemia,HG)、原发性高血压(primary hypertension,PHT)、血脂异常(dyslipidemia,DLP)及OB,尤其腹型肥胖(abdominal obesity,AOB)患病率升高,差异有统计学意义(P<0.05或P<0.01);②多元线性回归分析显示,对MAU贡献大小依次WTHR> WC> WHR;③采用受试者工作特征曲线(ROC)分析男性人群WTHR、WHR、WC等预测MAU的曲线下面积依次为0.68(95%CI:0.67 ~ 0.70)、0.64(95% CI:0.62 ~0.65)、0.57 (95% CI:0.55~0.59),预测切点0.52、0.90、91.8 cm.在女性人群中,WSR、WC、WHR等预测MAU的曲线下面积依次为0.71(95%CI:0.70~0.72)、0.69 (95% CI:0.68~0.70)和0.64(95% CI:O.62 ~0.65),预测切点0.52、0.84、82.5 cm.结论 ①AOB为MAU的高危人群;②WTHR为最佳预测指标,切点为0.52,其次为WC和WHR,男性切点分别为89.6 cm和0.88 cm,女性为84.5 cm和0.84 cm. Objectives To investigate the correlation between anthropometric obesity index and microalbuminuria (MAU).Methods Clinical data of 1170 cases were collected in the epidemiological survey database in 2012 chengyang district people's hospital of qingdao city.Urinary albumin(UAlb),urinary creatinine(UCr) and urinary albumin creatine rate(UACR) were randomly determined in the early morning,albumin creatine rate urinary (UACR) was calculated,,All patients were divided into normal albumin urine group (NAU group,398 males,409 femals) and microalbuminuria group (MAU group,175 males,188 females) according to the level of UACR.Anthropometric indexes and biochemical indexes were statistically analysed.Results ①Compared with the NAU group,age,fasting blood glucose(FBG),diastolic blood pressure (DBP),systolic blood pressure (SBP),serun urinary acid(SUA),waist circumference(WC),waist to height ratio(WTHR),waist to hip ratio (WHR) of the MAU group were higher than those of the NAU group,the difference was statistically significant (P 〈 0.05 or P 〈 0.01).Compared with the NAU group,high blood glucose,hypertension,dyslipidemia and obesity especially abdominal obesity prevalence rate of the NAU group increased,the difference was statistically significant (P 〈 0.05 or P 〈 0.01).②Multiple linear regression analysis was carried,the contribution to MAU was WTHR 〉 WC 〉 WHR in turn.③By Using the receiver operating characteristic curve (ROC) analysis,in male population,the predictive MAU area under the curve of WTHR,WHR,WC was 0.68 (95%CI:0.67 ~0.70),0.64 (95% CI:0.62 ~0.65),0.57 (95%CI:0.55 ~0.59),respectively.Predictive point was 0.52,0.90,91.8 cm.,in female population,the predictive MAU area under the curve of WTHR,WHR,WC was 0.71 (95 % CI:0.70 ~ 0.72),0.69 (95 % CI:0.68 ~ 0.70) and 0.64 (95 % CI:0.62 ~ 0.65),respectively.Predictive point was 0.52,0.84,82.5 cm.Conclusions ① The AOB population is
作者 徐美华 刘春妮 饶小胖 Xu Meihua, Liu Chunni, Rao Xiaopang. (Chengyang District People 's Hospital of Shandong Qingdao, Qingdao 266109, China)
出处 《国际泌尿系统杂志》 2017年第2期217-220,共4页 International Journal of Urology and Nephrology
基金 青岛市医疗卫生优秀人才培养计划(201502)
关键词 白蛋白尿 肥胖症 人体测量术 Albuminuria Obesity Anthropometry
作者简介 通讯作者:饶小胖Email:123raoxiaopang@163.com
  • 相关文献

参考文献5

二级参考文献29

  • 1江曼丽.糖基化作用与糖尿病慢性并发症[J].国外医学:内分泌学分册,1997,17(1):32-35. 被引量:54
  • 2李光伟.胰岛素敏感性评估及其在临床研究中的应用[J].中华内分泌代谢杂志,2000,16:198-198. 被引量:21
  • 3Mykkanen L, Zaccaro D J, Wagenknecht LE, et al.Microalbuminuria is associated with insulin resistance in nondiabetic subjects: The Insulin Resistance Atherosclerosis Study. Diabetes,1998, 47 : 793-800. 被引量:1
  • 4Hoy WE, Mathews JD, McCredie DA, et al. The multidimensional nature of renal disease: rates and a.ssiociations of albuminuria in an Australian Aboriginal community. Kidney Ira, 1998, 54 : 1296-1304. 被引量:1
  • 5Jager A, Kostense PJ, Nijpels G, et al. Microalbuminuria is strongly associated with NIDDM and hypertension, but not with the insulin resistance syndrome: the Hoom Study. Diabetologia,1998,41 : 694-700. 被引量:1
  • 6Bakris GL. Microalbuminuria: what is it? why is it important?what should be done about it? J Clin Hypertens, 2001,3 : 99-102. 被引量:1
  • 7Kim YI, Kim CH, Choi CS, et al. Microalbuminuria is associated with the insulin resistance syndrome independent of hypertension and type 2 diabetes in the Korean population. Diabetes Research and Clinical Practice, 2001,52 : 145-152. 被引量:1
  • 8World Health Organization. Definition, diagnosis and classification of diabetes mellitus and its complications. Report of a WHO consultation, Part 1: Diagnosis and classification of diabetes mellitus. WHO: Geneva, 1999. 被引量:1
  • 91999 World Health Organization-international society of hypertension guidelines for the management of hypertension.Guideline subcommittee. J Hypertens, 1999,17 : 151-183. 被引量:1
  • 10Rowley KG, Iser DM, Best JD, et al. Albuminuria in Australian Aboriginal people: prevalence and asscioations with components of the metabolic syndrome. Diabetologia,2000,43:1397-1403. 被引量:1

共引文献149

同被引文献11

引证文献2

投稿分析

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部 意见反馈