Objective： To explore the application of tomo direct（TD） technique in postoperative radiotherapy for patient with breast cancer received breast-conservative surgery so as to provide reference for clinical treatment. Methods： 30 patients received breast-conservative surgery were divided into tomo direct-conformal radiation therapy（TD-CRT group, TD-intensity modulated radiation therapy（TD-IMRT）group and IMRT group. The prescription dose was 50 Gy/25 F in planning target volume（PTV）. The doses of target region and organ at risk（OAR） were evaluated according to dose volume histogram（DVH）, and the execution efficiency was evaluated depended on the treatment time of different techniques. Results： The Dmean, D2, D98 and CI of TD-IMRT group was better than that of other groups, and the differences among them were significant（F=8.847, F=4.837, F=5.175, F=9.622; P〈0.05）, while the differences of HI among them were not significant. For OAR, the received dose of TD-IMRT group lower than that of other groups, and the differences among them were significant. The therapeutic time of TD-IMRT group was longer than that of TD-CRT group, while was obviously shorter than that of IMRT group. Conclusion： All of three techniques can satisfy the clinical requirement of postoperative radiotherapy for breast-conservative surgery. While the TD-IMRT technique has better dose distribution for target region, and its received dose of OAR is obviously lower, and its therapeutic time is reasonable. Therefore, TD-IMRT can be adopted as the optimal technique for postoperative radiotherapy of breast-conservative surgery.
China Medical Equipment
Tomo direct technique