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清肝健脾方对中青年H型高血压焦虑状态的影响 预览 被引量:1

Effect on H Type Hypertension with Anxiety State in Middle-Aged and Young Patients Treated with Qinggan Jianpi Decoction
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摘要 目的观察清肝健脾方对中青年H型高血压病焦虑患者的临床疗效及血浆同型半胱氨酸的影响。方法纳入符合中青年H型高血压伴有焦虑,中医证属肝郁脾虚型患者80例,采用完全区组随机法将患者分为对照组(西药常规治疗)和治疗组(清肝健脾方治疗),每组40例,两组疗程均28 d。观察两组焦虑评分、血浆同型半胱氨酸及肾素血管紧张素水平变化、动态血压下降幅度、中医证候积分对比。结果两组治疗后焦虑评分、中医证候积分较治疗前均下降,治疗组优于对照组(P〈0.05);两组治疗后血浆同型半胱氨酸、肾素血管紧张素、动态血压均明显下降(P〈0.01),治疗组优于对照组(P〈0.05)。结论清肝健脾方可改善中青年H型高血压病焦虑症状,并在降压的同时降低血浆同型半胱氨酸、肾素血管紧张素的水平。 Objective To observe the clinical efficacy and effect of plasma homocysteine( Hcy) on H type hypertension with anxiety state in middle-aged and young patients treated with Qinggan Jianpi decoction. Methods 80 middle-aged and young patients with H type hypertension were chosen and randomly divided into control group and treatment group with 40 cases in each group. The control group was treated with western medicine and the treatment group was treated with Qinggan Jianpi decoction. The two groups were treated for 28 days. The level of plasma homocysteine( Hcy) and renin-angiotensin system( RAS),score of symptom and anxiety and the change of blood pressure were observed. Results After treatment,the score of symptom and anxiety,the level of Hcy and RAS and ambulatory blood pressure were significantly decreased than that of before treatment in two groups and the degree of improvement of treatment group was superior to control group. Conclusions The Qinggan Jianpi decoction can obviously improve the anxiety state and is effective in reduction of blood pressure,levels of plasma homocysteine and the renin-angiotensin system in middle-aged and young patients with H-type hypertension with anxiety state.
作者 景国际 张翠 王国利 刘君 李敏静 尚菊菊 JING Guo - ji1 , ZHANG Cui1 , WANG Guo - li1 , LIU Jun1 , LI Min - jing1 , SHANG Ju - ju2 ( 1. Pinggu Hospital, Beijing Hospital of TCM, Beijing 100730 ;2 Beijing Hospital of Traditional Chinese Med- icine Affiliated to Capital Medical University,Beijing 100010)
出处 《世界中西医结合杂志》 2017年第6期814-817,共4页 World Journal Of Integrated Traditional and Wesrern Medicine
基金 国家中医药管理局国家中医临床研究基地业务建设科研专项(JDZX2015151) 北京市中医管理局薪火传承3+3黄丽娟名医工作站平谷分站
关键词 清肝健脾方 中青年H型高血压 焦虑 血浆同型半胱氨酸 Qinggan Jianpi decoction H type hypertension in middle-aged and young patients Anxiety Plasma homocysteine
作者简介 通讯作者:尚菊菊,Email:1823042511@qq.com
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