Objective To observe the clinical efficacy and effect of plasma homocysteine（ Hcy） on H type hypertension with anxiety state in middle-aged and young patients treated with Qinggan Jianpi decoction. Methods 80 middle-aged and young patients with H type hypertension were chosen and randomly divided into control group and treatment group with 40 cases in each group. The control group was treated with western medicine and the treatment group was treated with Qinggan Jianpi decoction. The two groups were treated for 28 days. The level of plasma homocysteine（ Hcy） and renin-angiotensin system（ RAS）,score of symptom and anxiety and the change of blood pressure were observed. Results After treatment,the score of symptom and anxiety,the level of Hcy and RAS and ambulatory blood pressure were significantly decreased than that of before treatment in two groups and the degree of improvement of treatment group was superior to control group. Conclusions The Qinggan Jianpi decoction can obviously improve the anxiety state and is effective in reduction of blood pressure,levels of plasma homocysteine and the renin-angiotensin system in middle-aged and young patients with H-type hypertension with anxiety state.
World Journal Of Integrated Traditional and Wesrern Medicine
Qinggan Jianpi decoction
H type hypertension in middle-aged and young patients