Objective To analyze the distribution characteristics and risk factors of nosocomial infection pathogens in Neonatal department. Methods From January 2013 to January 2017 in our hospital Neonatal department, the clinical data of 1320 children patients were retrospectively analyzed, including 160 cases of nosocomial infection. The types, characteristics and distribution of pathogenic bacteria were analyzed, and logistic regression was used to analyze the risk factors. Results In our hospital Neonatal department the infection rate was 2.65% （ 130/4900 ） , and the types of infection were mainly sepsis and pneumonia, accounting for 34.62% and 19.23%, which pathogens of gram negative bacteria were Klebsiella pneumoniae and Escherichia coli, accounting for 17.44% and 22.09% respectively, while gram-positive bacteria were mainly staphylococcus epidermidis and staphylococcus cocci, accounting for 14.53% and 8.14% respectively. Logistic regression analysis showed that gestational age〈37 weeks, birth weight〈lS00g, asphyxia rescue history, hospitalization time （7d） , mechanical ventilation, parenteral nutrition, invasive operation and the use of antibiotics and hormones （ more than 2 types ） were all the risk factors for nosocomial infection. Conclusions The main pathogens in Neonatal department are Klebsiella pneumoniae and Escherichia coll. The control of nosocomial infection and the prevention of neonatal asphyxia are very important, as well as The management and protection ofpreterm and very low birth weight infants.
Zhejiang Clinical Medical Journal
Neonate Nosocomial infection Pathogenic bacteria distribution Risk factors