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综合护理干预对产后抑郁症患者焦虑、抑郁生活质量、甲状腺功能及炎性因子的影响 预览 被引量:4

Effects of comprehensive nursing intervention on anxiety, depression, life quality, thyroid function and inflammatory factors of patients with postpartum depression
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摘要 目的 综合护理干预对产后抑郁症患者焦虑、抑郁、生活质量、甲状腺功能及炎性因子的影响。方法 产后抑郁症者104例,随机分为两组,对照组35例,观察组69例。对照组采用常规护理,观察组在常规护理的基础上采用针对性综合护理干预。妊娠28-32周开始对一周间出现情况进行抑郁评估。在诊断为抑郁症与护理干预3个月后采用焦虑自评量表(SAS)和抑郁自评量表(SDS)对患者进行焦虑、抑郁评价,SF-36中文版评估生活质量。抽晨起静脉血检测干预前后游离三碘甲状腺原氨酸(FT3)、游离甲状腺素(FT4)、促甲状腺素(TSH)、抗甲状腺过氧化酶抗体(TPO-Ab)及抗甲状腺球蛋白抗体(TG-Ab)、白介素-6(IL-6)、白介素-1β(IL-1β)、肿瘤坏死因子-α(TNF-α)、超敏C反应蛋白(hs-CRP)的水平变化。所获数据采用方差分析、t检验和χ^2检验。结果 对照组干预前后焦虑、抑郁评分比较,P均〈0.0005。观察组干预前后焦虑、抑郁评分比较,P均〈0.0005。两组干预后焦虑、抑郁评分比较,P均〈0.0005。同组干预前后及两组干预后生理功能、生理职能、情感职能、活力、躯体疼痛、社会功能、精神情况评分变化比较,P〈0.005-0.0005。对照组分娩3天和干预后FT3、FT4、TSH、TPO-Ab及TG-Ab水平变化比较,P均〉0.05。观察组分娩3天与干预后FT3、FT4、TSH水平变化比较,P均〉0.05。两组分娩3天与干预后TPO-Ab及TG-Ab水平变化比较,P均〉0.05。两组干预后FT3、FT4、TSH、TPO-Ab及TG-Ab水平变化比较,P均〉0.05。同组干预前后及两组干预后IL-6、IL-1β、TNF-α及hs-CRP水平变化比较,P均〈0.0005。两组产妇的精神状态、纯母乳喂养、健康知识掌握、子宫复旧情况比较,P均〉0.05。对照组产褥期并发症率20.00%,观察组产褥期并发症率2.90%。两组比较,P〉0.05。结论 综合护理干预对产后抑郁症患者焦虑、抑郁、生活质 Objective To study the effect of comprehensive nursing intervention on anxiety, depression, quality of life, thyroid function and inflammatory factors of patients with postpartum depression. Methods 104 cases of postpartum depression patients were randomly divided into two groups, 35 cases in the control group and 69 cases in the observation group. The control group was given routine nursing. The observation group was treated with comprehensive nursing intervention based on routine nursing. Depression was assessed at 28 to 32 weeks of gestation. Three months after diagnosis of depression and nursing intervention, anxiety and depression were evaluated by self-rating anxiety scale(SAS) and self-rating depression scale(SDS). SF-36 Chinese version was used to evaluate the quality of life. The levels of free triiodothyronine(FT3), free thyroxine(FT4), thyrotropin(TSH), antithyroid peroxidase antibody(TPO-Ah) and antithyroid globulin antibody(TG-Ab), interleukin-6(IL-6), interleukin-1β (IL-1β ), tumor necrosis factor-α (TNF-α ) and high sensitivity C- reactive protein(hs-CRP) were detected before and after the intervention. The data were analyzed by variance analysis, t test and χ^2 test. Results The scores of anxiety and depression in the control group were compared before and after intervention, P〈0.0005. The scores of anxiety and depression in the observation group were compared before and after intervention,P〈0.0005. The scores of anxiety and depression were compared between the two groups after intervention, P〈0.0005. The scores of physiological function, physiological function, emotional function, vigor, physical pain, social function and mental condition in the same group before and after intervention and after intervention were compared P〈0.005-0.0005. The levels of FT3, FT4, TSH, TPO-Ab and TG-Ab in the control group were compared with those in the control group 3 days after delivery P〉0.05. The levels of FT3, FT4, TSH in the observation group were com
作者 马巧真 Ma Qiaozhen (Heze Maternal and Child healthcare and Family Planning Service Center, Heze 274000, Shandong)
出处 《菏泽医学专科学校学报》 2018年第1期71-75,共5页 Journal of Heze Medical College
关键词 综合护理 产后抑郁症 焦虑 抑郁 生活质量 甲状腺功能 炎性因子 Comprehensive nursing Postpartum depression Anxiety Depression Quality of life Thyroid function Inflammatory factor
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