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鼻内镜术中布地奈德混悬液浸润对慢性鼻-鼻窦炎患者术后焦虑情绪及鼻腔相关功能恢复的影响 被引量:1

Effect of Budesonide Suspension Infiltration on Anxiety and Recovery of Nasal Related Function in Patients with Chronic Rhinosinusitis after Nasal Endoscopic Surgery
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摘要 目的:探讨鼻内镜手术应用布地奈德混悬液浸润对慢性鼻-鼻窦炎(CRS)患者术后焦虑情绪及鼻腔相关功能恢复的影响。方法:随机数字表格法将120例CRS患者分为观察组与对照组各60例,观察组于鼻内镜手术完成时将含有布地奈德混悬液浸润的明胶海绵置入中鼻道,对照组仅放置明胶海绵(不含药物),比较两组治疗前后视觉模拟评分(VAS)、鼻窦CT评分、鼻黏膜纤毛功能及焦虑自评量表(SAS)情况。结果:观察组术后4周总体症状VAS评分、鼻窦CT评分、SAS评分均显著低于对照组,差异有统计学意义(t=-2.590,-3.548,-5.735;P〈0.05);黏膜纤毛清除率、黏膜纤毛清除速度及糖精清除时间方面,观察组均显著优于对照组(t=5.336,3.828,-7.131;P〈0.05)。结论 :鼻内镜手术应用布地奈德混悬液浸润能明显改善CRS患者术后鼻黏膜纤毛功能及鼻部症状,术后焦虑情绪显著轻。 Objective:To investigate the effect of budesonide suspension infiltration on anxiety and recovery of nasal related function in patients with chronic rhinosinusitis(CRS)after nasal endoscopic surgery.Methods:A total of 120 patients with CRS were divided into the observation group and the control group by random number table method with 60 patients in each group.In the observation group,the gelatin sponge impregnated with budesonide suspension was placed in the middle meatus of patients at the end of nasal endoscopic surgery,while in the control group,only gelatin sponge(without drugs)was placed.The visual analogue scale(VAS)scores,sinus CT scores,nasal mucociliary function and the self rating Anxiety Scale(SAS)scores were compared between the two groups before and after treatment.Results:The overall VAS score,sinus CT score and SAS score of the observation group were significantly lower than those of the control group at 4 weeks after surgery(t=-2.590,-3.548,-5.735;P〈0.05).The mucociliary clearance rate,mucociliary clearance speed and saccharin clearance time in the observation group were significantly better than those in the control group(t=5.336,3.828,-7.131;P〈0.05).Conclusion:The use of budesonide suspension infiltration can obviously improve the nasal mucociliary function and relieve nasal symptoms in patients with CRS after nasal endoscopic surgery,and the degree of anxiety after surgery is mild.
作者 刘喜亮 LIU Xiliang (E.N.T.Department ,Yingcheng People's Hospital ,Yingcheng 432400, China)
出处 《中国健康心理学杂志》 2018年第8期1200-1203,共4页 china journal of health psychology
关键词 慢性鼻-鼻窦炎 布地奈德混悬液 焦虑情绪 鼻黏膜纤毛功能 Chronic rhinosinusitis Budesonide suspension Anxiety Nasal mucociliary function
作者简介 E-mail:liuxiliangac@sina.com
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