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^18F-FDG PET/CT在Ⅲ/Ⅸ期黑色素瘤转移中的应用价值 预览

The value of ^18F-FDG PET/CT on metastasis for stage Ⅲ/Ⅸ malignant melanoma
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摘要 目的探讨正电子发射计算机断层显像(PET)在Ⅲ/Ⅳ期黑色素瘤转移中的应用价值。方法对经临床病理证实的黑色素瘤的9例患者行PET/CT检查,随访经3月的影像或病理资料证实为AJCC分期为Ⅲ/Ⅳ期,计算PET/CT与常规CT对于淋巴结及转移灶的检出率,应用SPSS 17. 0软件行配对资料X2检验,比较检出率的差异,并分别计算真阳性率与假阳性率之比。结果 PET/CT对淋巴结转移灶的检出率明显高于CT分别为91. 67%和37. 50%,差异有统计学意义(X2=6. 231,P=0. 014),真假阳性率之比分别为5. 50和1. 12。PET/CT对远处转移灶的检出率(92. 11%)也高于常规CT(64. 47%),差异有统计学意义(χ2=5. 944,P=0. 018),真假阳性率之比5. 83及1. 26。结论 PET/CT能是一种较好的检测黑色素瘤转移灶的方法,较常规CT有较大优势。 Objective To explore the value for ^1 F-fluoro-deoxy-2-glocuse(^18F-FDG) PET-CT on metastasis for stage Ⅲ/Ⅸ malignant melanoma. Methods PET/CT was examined in 9 patients with clinically confirmed malignant melanom. After 3 months of follow-up,imaging or pathological data confirmed that the American Joint Committee on Cancer(AJCC) stage was Ⅲ/Ⅳ. The detection rates of lymph node and metastasis were calculated by PET/CT and conventional CT,the difference of detection rate was compared by using SPSS 17 paired data and chi 2 test,and the ratio of truly to false positive was calculated. Results The detection rates of lymph node metastasis by CT and PET/CT were respectively 37. 5% and 91. 67%,the ratio of truly to false positive was 1. 12 and 5. 50 respectively. For distant metastases,the detection rates were 64. 47% and 92. 11%,the ratio of truly to false positive was 1. 26 and 5. 83 respectively. The detection rate of PET/CT in lymph node metastasis and distant metastasis was significantly higher than that of conventional CT,the difference was both statistically significant(χ2= 6. 231,P = 0. 014; χ2= 5. 944,P = 0. 018). Conclusion PET/CT is a better method for detecting metastasis of malignant melanoma,and had obviously advantage than conventional CT.
作者 郭满涛 欧阳翠微 刘连峰 魏春燕 张涛 GUO Mantao, OUYANG Cuiwei, LIU Lianfeng, WEI Chunyan, ZHANG Tao (Imaging Department, Xianyang Hospital of Yan'an University, Xianyang 712000, P. R. China)
出处 《医学影像学杂志》 2018年第8期1371-1374,共4页 Journal of Medical Imaging
关键词 恶性黑色素瘤 ^18F-FDG 正电子发射断层显像 转移灶 Malignant melanoma ^18F-FDG Positron emission tomography Metastasis
作者简介 郭满涛(1982-),男,陕西户县人,毕业于中国医科大学,医学硕士,主治医师,主要从事肿瘤影像诊断工作;通信作者:欧阳翠微,主治医师E-mali:3201682057@qq.com
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