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肺部5cm以下不同大小炎性肉芽肿和恶性病灶SUVmax的差异性研究 预览

A study on the difference of SUVmax between pulmonary inflammatory granulomas and malignant lesions of different sizes below 5cm
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摘要 目的对肺部5cm以下不同大小炎性肉芽肿和恶性病灶代谢特点进行研究,评价最大SUV(SUVmax)对肺部炎性肉芽肿和恶性病灶的诊断价值。方法回顾性分析138例患者的临床及影像资料。测量病灶的最大径及SUVmax刚按照病灶最大径分为5组,即≤1cm组、1~2cm组、2~3cm组、3~4cm组、4~5cm组。采用SPSS20.0软件进行统计学分析。结果3cm以下各组炎性肉芽肿SUVmax;均高于恶性病变,且差异均有统计学意义;3~4cm组炎性肉芽肿与恶性病变SUVmax大致相仿,炎性肉芽肿稍高,但差异无统计学意义;4~5cm组恶性病变SUVmax。高于炎性肉芽肿,且差异有统计学意义。结论SUVmax对诊断肺部病灶的良恶性有一定价值,但临床诊断时还必须注意SUVmax与病灶大小的关系,同时须结合高分辨率CT(HRCT)的征象进行综合诊断,方能提高诊断的准确性。 Objective To study metabolic characteristics of pulmonary inflammatory granulomas and malignant lesions of different sizes below 5 cm and evaluate diagnostic value of SUVmax for inflammatory granulomas and malignant lesions. Methods The clinical and imaging data of 138 patients were retrospectively analyzed. The maximum diameter and SUVmax were measured. The lesions were divided into 5 groups according to the maximum diameter, including 〈 1 cm, 1 - 2 cm, 2 - 3 cm, 3 - 4 cm and 4 - 5 cm group. SPSS 20.0 software was used for statistical analysis. Results The SUVmax values of inflammatory granulomas below 3 cm were all higher than those of malignant lesions, and the differences were statistically significant. The SUVmax of inflammatory granulomas in 3 - 4 cm was similar to malignant lesions and the SUVmax of inflammatory granulomas was slightly higher, but the difference was not statistically significant. The SUVmax of malignant lesions in 4 - 5cm was higher than that of inflammatory granulomas, and the difference was statistically significant. Conclusions The SUVmax is a diagnostic indicator of benign and malignant pulmonary lesions. The relationship between the SUVmax and the size of the lesion must be paid attention to in the clinical diagnosis. At the same time, the diagnostic accuracy can be improved by combining with the signs of HRCT.
作者 邓凯吉 陈自谦 赵春雷 付丽媛 林晨琳 DENG Kaiji, CHEN Ziqian, ZHAO Chunlei, FU Liyuan, LIN Chenlin( Medical Imaging Center, Fuzhou General Hospital of PLA, Fuzhou 350025, China)
出处 《功能与分子医学影像学(电子版)》 2018年第2期1442-1449,共8页 Functional and Molecular Medical Imaging(Electronic Edition)
基金 国家重点研发计划数字诊疗装备研发重点专项子课题(2016YFC0103103)
作者简介 邓凯吉,医学硕士,住院医师。主要从事影像诊断工作;[通讯作者]陈自谦,Email:chenziqianfz@sina.com
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