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3.0T磁共振在脑白质疏松症及多发性硬化鉴别诊断中应用分析

Application of 3 T Magnetic Resonance Imaging in Differential Diagnosis of Leukoaraiosis and Multiple Sclerosis
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摘要 目的:探讨3.0T磁共振(Medical Resonance Imagin,MRI)在脑白质疏松症(Leukoaraiosis,LA)及多发性硬化(Multiple Sclerosis,MS)鉴别诊断中的应用效果。方法:选择医院确诊的42例MS和64例LA患者,均采用常规3.0TMRI与弥散张量成像(Diffusion tensor imaging,DTI)检查,比较MS与LA患者的PVH分型以及不同分型FA值与ADC值的变化情况,分析PVH分级1型中不同部位脑白质病灶FA值与ADC值的差异。结果:LA组PVH分型较MS组严重,差异有统计学意义(P〈0.05);PVH分级越高,MS与LA的表观扩散系数(Apparent diffusion coefficient,ADC)值呈逐渐增高趋势(r=0.641、0.785,P=0.002、0.000),部分各向异性(Fraction anisotropy,FA)值呈逐渐降低趋势(r=-0.415、-0.582,P=0.005、0.006);PVH分级1型中LA组侧脑室后角周围白质区、侧脑室前角周围白质区、放射冠FA值以及放射冠ADC值均低于MS组,差异具有统计学意义(P〈0.05);LA组侧脑室后角周围白质区、侧脑室前角周围白质区ADC值低于MS组,差异无统计学意义(P〉0.05)。结论:3.0TMRIDTI检查可较为准确的鉴别早期LA与MS病灶,为临床早期诊治MS提供参考依据。 Objective: To investigate the application of 3.0 T magnetic resonance ( Medical Resonance Imagin, MRI ) in the differential diagnosis of leukoaraiosis ( Leukoaraiosis, LA ) and multiple sclerosis ( Multiple Sclerosis, MS ). Methods: 42 patients with MS and 64 LA patients diagnosed were examined by routine 3 TMRI and diffuse tensor imaging ( Diffusion tensor imaging, DTI ). The changes of PVH sub-types of MS and LA patients and the changes of FA values and ADC values were compared. The difference between the value and the ADC value. Results: The PVH clas- sification in group IrA was more serious than that in group MS, and the, difference was statistically significant ( P〈0.05 ). The higher the PVH classification, the apparent diffusion coefficient ( Apparent diffusion coefficient, ADC ) of MS and LA increased gradually ( r=0.641, 0.785, 0 ), and the value of partial anisotropy decreased gradually. The poten- tial ( r=-0.415, -0.582, P=0.005, 0.006 ), the white matter around the posterior horn of the lateral ventricle, the white matter around the anterior horn of the lateral ventricle, the FA value of the radiated crown and the ADC value of the radiation crown in the LA group of the LA group were lower than those in the MS group, and the difference was statisti- cally significant ( P〈0.05 ) ; the peripheral ventricle around the lateral ventricle and the white matter around the lateral ventricle of the lateral ventricle of the LA group were in the white matter area. The ADC value was lower than that of MS group, and the difference was not statistically significant ( P〉0.05 ). Conclusion: 3.0T MRI DTI examination can accurately identify early LA and MS lesions, and provide reference for early diagnosis and treatment of MS.
作者 蒋秀丽 李文清 J1ANG Xiuli1, LI Wenqing2 (1. Xunxian County Hospital of Traditional Chinese Medicine, Henan Hebi 456250, China; 2. Anyang People's Hospital, Henan Anyang 455000, China)
出处 《中医药临床杂志》 2018年第9期1648-1650,共3页 Clinical journal of traditional chinese medicine
关键词 多发性硬化 脑白质疏松症 3.0T MRI 鉴别诊断 Multiple sclerosis Leukoaraiosis 3.0T MRI Differential diagnosis
作者简介 蒋秀丽(1980-)女,主治医师。研究方向:脑血管疾病方向的影像学诊断方向。E-msil:jiangxiulihnxx@163.com
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