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结扎亚甲蓝染色后淋巴管对盆腔淋巴囊肿形成的影响 预览

Effect of lymphatic vessels on the formation of pelvic lymphocyst after ligation of methylene blue staining
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摘要 目的分析结扎亚甲蓝染色后淋巴管对盆腔淋巴囊肿形成的影响。方法选取2017年1月~2018年6月于我院行盆腔淋巴结切除术的86例妇科恶性肿瘤患者作为研究对象,根据随机数字表法将其分为研究组和对照组,每组各43例。研究组患者行亚甲蓝示踪淋巴管后结扎盆腔淋巴管,对照组患者行常规结扎盆腔淋巴管。比较两组患者术后不同时段盆腔淋巴囊肿形成情况及并发症发生情况(伤口感染、发热、深静脉血栓形成、肠梗阻、会阴肿胀),并观察研究组患者的亚甲蓝不良反应发生情况。结果研究组患者术后1、4周的盆腔淋巴囊肿发生率均低于对照组,差异有统计学意义(P<0.05);研究组患者术后12、24周的盆腔淋巴囊肿发生率均低于对照组,但差异无统计学意义(P>0.05)。研究组患者的术后并发症总发生率低于对照组,但差异无统计学意义(P>0.05)。研究组患者注射亚甲蓝注射液后未见晕眩、呕吐、胸闷、感染、血压降低等不良反应。结论结扎亚甲蓝染色后淋巴管可降低盆腔淋巴囊肿发生率,同时可降低不良反应,值得临床推广应用。 Objective To analyze the effect of lymphatic vessels on the formation of pelvic lymphocyst after ligation of methylene blue staining.Methods A total of 86 patients with gynecologic malignancies who underwent pelvic lymphadenectomy from January 2017 to June 2018 were selected as research objects,and the patients were divided into the study group and the control group according to the random number table method,with 43 cases in each group.Patients in the study group underwent methylene blue to trace the lymphatic vessels and then the pelvic lymphatic vessels were ligated,and the pelvic lymphatic vessels were routinely ligated in the control group.The pelvic lymphocyst formation and complications(wound infection,fever,deep vein thrombosis,intestinal obstruction,perineal swelling)were compared between the two groups at different time points,and the incidence of methylene blue adverse reactions in the study group was observed.Results The incidence rates of pelvic lymphocysts at 1 week and 4 weeks after operation in the study group were lower than those in the control group,and the differences were statistically significant(P<0.05).The incidence rates of pelvic lymphocysts at 12 and 24 weeks after operation in the study group were lower than those in the control group,but the differences weren′t statistically significant(P<0.05).The total incidence rate of postoperative complications in the study group was lower than that in the control group,but the difference was not statistically significant(P>0.05).In the study group,no adverse reactions such as dizziness,vomiting,chest tightness,infection,and blood pressure were observed after the injection of Methylene Blue Injection.Conclusion Lymphatic vessels after ligation of methylene blue staining can reduce the incidence of pelvic lymphocyst,and at the same time it can reduce adverse reactions,which is worthy of clinical promotion and application.
作者 胡萍 彭蔚 吴名桃 刘婷 王文华 HU Ping;PENG Wei;WU Ming-tao;LIU Ting;WANG Wen-hua(Department of Gynecology,Pingxiang People′s Hospital,Jiangxi Province,Pingxiang 337000,China)
出处 《中国当代医药》 2019年第2期101-103,116共4页 China Modern Medicine
基金 江西省卫生计生委科技计划项目(20187208).
关键词 妇科恶性肿瘤 盆腔淋巴囊肿 淋巴管 结扎术 亚甲蓝染色 Gynecological malignancy Pelvic lymphocyst Lymphatic vessel Ligation Methylene blue staining
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