Objective To compare the clinical efficacy of cefoperazone and amikacin in the treatment of acute pyelonephritis. Methods 96 patients with acute pyelonephritis admitted to our hospital from May 2016 to April 2018 were randomly divided into the control group (48 cases) and the study group (48 cases).The control group received amikacin.Intravenous infusion of natamycin injection,the study group was given intravenous infusion of cefoperazone injection,and the clinical efficacy,urine culture conversion rate and adverse reaction rate of different groups were compared. Results The total effective rate of clinical treatment and the negative rate of urine culture in the study group were higher than those in the control group, but the difference between the two groups was not significant ( P > 0.05).The incidence of adverse reactions in the study group was significantly lower than that in the control group.Significant ( P < 0.05). Conclusion Amikacin and cefoperazone are equally effective in the treatment of acute pyelonephritis, but the latter has a lower incidence of adverse reactions.
Journal of Clinicl Medical Literature ( Electronic Edition )