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miRNA-29调控乳腺癌发生发展的研究进展 预览

Research progress of miRNA-29 in tumorigenesis and progression of breast tumor
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摘要 miRNA-29(miR-29)家族是微小RNA(microRNAs,miRNAs)家族成员,包括miR-29a、miR-29b和miR-29c,已有报道在多种癌症中异常表达。更多证据表明异常的miR-29表达与肿瘤的发生发展有关,因此,miR-29s是癌症研究中分析良好的一组miRNAs。最新研究表明,miRNA-29作为医学生物领域中重要的肿瘤分子标志物,在乳腺癌的发生、发展进程中发挥着重要作用。本文对miRNA-29调控乳腺癌发生、发展的作用予以概述。 The miRNA-29 family of microRNAs (miRNAs), including miR-29a, miR-29b and miR-29c, were recently reported to be aberrantly expressed in multiple cancers. Increasing evidence shows that the abnormal expression of miR-29 family is associated with tumorigenesis and cancer progression, making miR-29s a well-analyzed group of miRNAs in cancer research. Recently, it has been found that miRNA-29 family, an important molecular tumor markers in the field of medicalbiotechnology, showing significant differential expression in the development of breast cancer process. To make a review on the recent progress of miRNA-29 roles in tumorigenesis and cancer progression of breast cancer.
作者 张沿君 石代红 刘健 Zhang Yanjun;Shi Daihong;Liu Jian(Department of Breast Surgery, Yongchuan Hospital of Chongqing Medical University, Chongqing, 402160, China)
出处 《当代医学》 2019年第8期183-184,共2页 Contemporary Medicine
关键词 miRNA-29 乳腺癌 肿瘤发生 肿瘤侵袭 miRNA-29 Breast cancer Tumorigenesis Progression
作者简介 通讯作者:石代红,E-mail:543457821@qq.com;通讯作者:刘健,E-mail:1024908832@qq.com.
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