Endometriosis(EMs) is a common disease that seriously perplex the women of childbearing age at present. Because of its complicated pathogenesis, unknown etiology and characteristics of easy implantation and recurrence similar to tumor, there is still no definite diagnosis and treatment strategies for EMs. Recent studies have found that EMs is an autoimmune disease and closely related to T cell immunity. The helper T cell(Th) 17 and regulatory T cell(Treg) are two important subtypes of CD4~+T cells. The imbalance of Th17/Treg and imntraperitoneal environment affected by the imbalance of two cells proportion are related to the occurrence and degree of EMs, and also related to infertility of EMs. In this article, we focus on the latest research status of Th17/Treg and immune-internal environment imbalance in EMs.
Chinese JOurnal of Obstetrics & Gynecology and Pediatrics