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危重川崎病的诊治研究进展

Progress in diagnosis and treatment of severe Kawasaki disease
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摘要 川崎病(Kawasaki disease,KD)是好发于5岁以下儿童的急性全身性中小血管炎性综合征,其最严重的并发症是冠状动脉病变,可导致冠状动脉扩张、心肌梗死及猝死。已有研究报道,在KD急性期可出现与休克相关的严重临床表现,并可能涉及所有器官,称为危重症KD(severe Kawasaki disease,SKD),有时需要儿童重症监护病房的处理。虽然SKD患儿临床症状严重,但只要能精确诊断和快速治疗,大部分患者都能存活,且可没有任何后遗症。近年来,国内外学者对SKD的关注越来越多,基于此,我们将SKD作为研究对象,阐述其临床诊断和治疗的相关进展,以利于儿科临床医生精准判断和治疗相关疾病。 Kawasaki disease (KD) is an acute systemic small and medium vasculitis syndrome, which is most commonly found in children under the age of 5 years.The most severe complications of KD are coronary artery lesions (CAL), which will lead to coronary artery dilatation, myocardial infarction and sudden death.In the acute stage, severe clinical manifestations are associated with shock, and all organs could be involved, which is called severe Kawasaki disease (SKD), sometimes requiring treatment in the pediatric intensive care unit (PICU) have been reported.Although the clinical symptoms of children with SKD are severe, most patients can survive without any sequelae as long as they can be diagnosed accurately and treated rapidly.In recent years, scholars at home and abroad have paid more and more attention to SKD.Based on these, we take SKD as the research object, try to explain the progress of clinical diagnosis and treatment, which is beneficial to pediatric clinicians to accurately judge and treat related diseases.
作者 赵玉琪(综述) 谢利剑(审校) Zhao Yuqi;Xie Lijian(Department of Cardiology, Shanghai Children's Hospital, Shanghai Jiaotong University, Shanghai 200062, China)
出处 《国际儿科学杂志》 2019年第2期81-83,共3页 International Journal of Pediatrics
基金 上海市人才发展资金项目(201615) 上海市卫生局面上课题项目(No-201540099) 上海市儿童医院(2018YQN006).
关键词 川崎病 危重川崎病 冠状动脉损害 川崎病休克综合征 Kawasaki disease Severe Kawasaki disease Coronary artery lesions Kawasaki disease shock syndrome
作者简介 通信作者:谢利剑,Email:naijileix@aliyun.com.
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