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两种剂量排石汤治疗胆总管结石ERCP术后患者的临床研究 预览

Clinical Study on Two Different Dosages of Modified PaiShi Decoction or Choledocholith Patients after ERCP
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摘要 目的:比较2种剂量排石汤对胆总管结石ERCP术后疗效的影响。方法:将65例患者随机分为小剂量组(37例)和大剂量组(38例),2组均在ERCP取石后24小时服用不同剂量的排石汤治疗,连续治疗4天后行血生化、胆汁生化检测。结果:胆汁总胆汁酸、总胆固醇、钙离子、黏蛋白、直接胆红素、间接胆红素等治疗前后2组组内比较,差异均有统计学意义(P<0.05);总胆汁酸、总胆固醇、钙离子和黏蛋白等治疗后2组间比较,差异无统计学意义(P>0.05);直接胆红素、间接胆红素治疗后2组间比较,差异有统计学意义(P<0.05)。血直接胆红素、间接胆红素2组组内比较,差异均有统计学意义(P<0.05);生化指标治疗后2组组间比较,差异无统计学意义(P>0.05)。结论:小剂量排石汤更有助于改善胆总管结石ERCP术后患者直接胆红素和间接胆红素水平。 Objective:To compare the influence of two different dosages of PaiShi decoction on clinical effects of choledocholith after ERCP.Methods:All 65 patients were randomized into small dosage group(37 cases)and large dosage group(38 cases),both groups took different dosages of PaiShi decoction within 24 hours after removing calculus by ERCP,biochemical indicators of the bile and blood were detected after they were treated for four days consecutively.Results:When total bile acid(TBA),total cholesterol(TC),calcium ion,mucoprotein,conjugated bilirubin,unconjugated bilirubin and others were compared within two groups before and after treating,the difference was statistically significant(P<0.05);the difference had no statistical meaning in the comparisons of TBA,TC,calcium ion,mucoprotein and others(P>0.05);the difference showed statistical meaning in the comparisons of conjugated bilirubin and unconjugated bilirubin between both groups(P<0.05).the comparisons of conjugated bilirubin and unconjugated bilirubin within two groups(P<0.05);the difference had no statistical meaning in the comparisons of biochemical indicators between both groups after treating(P>0.05).Conclusion:Small dosage of PaiShi decoction is more helpful to improve the levels of conjugated bilirubin and unconjugated bilirubin in choledocholith patients after ERCP.
作者 李璐璐 黄晓俊 肖吉元 高丽萍 王祥 孔桂香 李丹 郝晋雍 LI Lulu;HUANG Xiaojun;XIAO Jiyuan;GAO Liping;WANG Xiang;KONG Guixiang;LI Dan;HAO Jinyong(Lanzhou University Second Hospital,Lanzhou 730030,China)
出处 《西部中医药》 2019年第2期101-103,共3页 Western Journal of Traditional Chinese Medicine
关键词 胆总管结石 ERCP 排石汤 小剂量 大剂量 choledocholith ERCP PaiShi decoction small dosage large dosage
作者简介 李璐璐(1985-),女,硕士学位,主治医师。研究方向:消化系统疾病的中西医结合诊治;通讯作者:黄晓俊(1962-),男,硕士学位,主任医师。研究方向:消化系统疾病的中西医结合诊治。
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