期刊文献+

A-PRF膜促进种植体周围附着龈再生的临床研究

Effect of A-PRF membrane on promoting regeneration of attached gingival around dental implants
分享 导出
摘要 目的:将富血小板纤维蛋白(advanced platelet-rich fibrin, A-PRF)膜应用于前庭沟加深术,探讨其促进种植体周附着龈再生的临床效果。方法:收集2015年10月─2017年7月在本院因种植体周附着龈不足而需前庭沟加深术的患者共26例,运用统计学中简单随机方法将患者随机分为2组(n=13),实验组应用A-PRF膜,对照组仅采用常规手术。术后不同时间点对附着龈再生、黏膜状态、疼痛程度进行评价。采用SPSS 17.0软件包对数据进行统计学分析。结果:术后2周、12周,实验组新增附着龈分别为(3.15±0.36)mm和(2.81±0.36)mm,均显著高于对照组的(2.93±0.29)mm和(2.52±0.30)mm(P<0.05)。实验组术后黏膜愈合状态也显著优于对照组(P<0.05)。实验组术后3 d疼痛程度为(51.03±12.20)分,与对照组(58.22±9.86)分比较显著降低(P<0.05)。结论:A-PRF膜应用于前庭沟加深术可有效促进创口愈合,缓解术后疼痛,并增加种植体周附着龈再生。 PURPOSE: Advanced platelet-rich fibrin(A-PRF) was applied in vestibular extension surgery to explore its effect on promoting regeneration of attached gingival around dental implants. METHODS: Twenty-six patients with insufficient attached gingiva around dental implants were enrolled in this study from October 2015 to July 2017, they were randomly divided into two groups(n =13). The experimental group received vestibular extension surgery with A-PRF membrane covering the wound, while the control group only received routine surgery. Increase of attached gingival, mucosa healing status and pain intensity were evaluated at different time points after surgery. SPSS 17.0 software package was used for statistical analysis. RESULTS: In the experimental group, increase of attached gingival at 2 and 12 weeks was(3.15±0.36) mm and(2.81±0.36) mm respectively, which was significantly higher than those [(2.93 ±0.29) mm and(2.52±0.30) mm] in the control group(P<0.05). The mucosa healing status in the experimental group at 2 and 12 weeks was also significantly better than that in the control group(P<0.05). Visual analogue scale(VAS) of pain in the experimental group was 51.03±12.20, which was significantly lower than that(58.22±9.86) in the control group(P<0.05). CONCLUSIONS:Application of A-PRF membrane in vestibular extension surgery could effectively promote mucosa healing, relieve postoperative pain and increase attached gingival regeneration around dental implants.
作者 马晓玉 冯晓洁 戚孟春 王艺睿 董伟 杜硕 MA Xiaoyu;FENG Xiao-jie;QI Meng -chun;WANG Yi-rui;DONG Wei;DU Shuo(College of Stomatology, North China University of Science and Technology,Tangshan 063210, Hebei Province, China)
出处 《中国口腔颌面外科杂志》 CAS 2019年第2期146-149,共4页 China Journal of Oral and Maxillofacial Surgery
基金 华北理工大学研究生创新项目.
关键词 富血小板纤维蛋白 附着龈 牙种植 种植体周围炎 前庭沟加深术 Advanced platelet-rich fibrin Attached gingival Dental implants Peri-implantitis Vestibular extension surgery
作者简介 马晓玉(1992-),女,硕士研究生.E-mail:120362702@qq.com;通信作者:戚孟春,E-mail:qimengchun@163.com.
  • 相关文献

参考文献5

二级参考文献27

  • 1Zuk PA, Zhu M, Mizuno H, et al. Muhilineage cells from human adipose tissue: hnp|ocation for cel|-based therapies [J]. Tissue Eng, 2001, 7(2): 211 -228. 被引量:1
  • 2Dhan DM, Ctlmkmlal J, Di,s A, el al. Platelel-rich l'ihrin (PI{F) : A se('md-eneration platelel on'entrale. Part I1: Plalelel-related hihgi: features[ J ]. Oral Surg Ol:al Med O- ral Pathol Oral Radhl Endued, 2006,101 (3):e45- eS0. 被引量:1
  • 3Halvorsen YD, Franklin D, Bond AI,, el al. Extraeellular matrix mineralization and usieoblast gene expression bv hu- man tissue-derived slromal cells [ J ]. Tissue Eng, 2001 , 7 (6) :729 -741. 被引量:1
  • 4Huang Jl, Beanes SR, Zhu M, el al. Rat extramedullary adipose tissue as a source of ostepchondrogenic progenitor cells[J]. Plast Reconstr Surg, 2002, 109 (3) : 1033 - 1041. 被引量:1
  • 5Hicok KC, Du Laney TV, Zhou YS, et al. Human adipose- derived aduh stem cells produce osteoid in vivo[ J ]. Tissue Eng, 2004, 10(3 -4) : 371 -380. 被引量:1
  • 6Cowan CM, Shi YY, Aalami 00, el al. Adipose-derivd a- duh stromal cells heal critical-size mouse calvarial detects[ .I ]. Nat Biotechnol, 2004,22 ( 5 ) : 560 - 567. 被引量:1
  • 7Dohan DM, Choukroun J, Diss A, el al. Plateh't-ri'h fil)rin (PRF) : A second-generation platelet COl,.entrat. P.ll'l II1: Leucocyte activation: A new feature for platelet concen- trates? [J]. Oral Su,'g Oral Med Oral Palhol Oral Radiol Endod, 2006,101 (3) :e51 -55. 被引量:1
  • 8Dohan DM, Choukroun J, Diss A, e! al. Platelet-rieh fibrin (PRF): A second-generation platelet concenlrate. Part 1: Technological concepts and evolution [J]. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006, 101 ( 3 ) : e37 - 44. 被引量:1
  • 9Dohan Ehrenfest DM, de Peppo GM, Doglidi P,et al. Slow release of growth factors and thrombospondin- 1 in Choukroun g platelet-rich fibrin (PRF) : A gohl standard to achieve for all surgical platelet concentrates technologies [ J ]. Growth Factors, 2009,27( 1 ) :63 -69. 被引量:1
  • 10刘南霞,赵寅华,张旻,陈永进.富血小板纤维蛋白对牙髓干细胞体外增殖与分化特性的影响[J].牙体牙髓牙周病学杂志,2013,23(9):558-563. 被引量:4

共引文献10

投稿分析

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部 意见反馈