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无创呼吸机治疗慢性阻塞性肺疾病急性加重期合并2型糖尿病效果及安全性 预览

Effect and Safety of Non-invasive Ventilator in the Treatment of Acute Exacerbation of Chronic Obstructive Pulmonary Disease with Type 2 Diabetes
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摘要 目的总结并分析慢性阻塞性肺疾病急性加重期合并2型糖尿病患者应用无创呼吸机治疗的临床效果及治疗安全性。方法50例样本分析对象都是2017年1月—2018年10月在该医院进行治疗的慢性阻塞性肺疾病急性加重期合并2型糖尿病患者,以计算机表法实现各组处理。试验组(n=25例)选择无创呼吸机治疗,对照组(n=25例)进行常规治疗,比较两组患者的治疗效果及治疗安全性。结果该实验探究中试验组患者的血糖指标:糖化血红蛋白(6.41±0.56)%(t=6.0254,P=0.0000)、餐后2h血糖(6.21±1.44)mmol/L(t=6.0872,P=0.0000)、空腹血糖(9.48±1.55)mmol/L(t=7.4714,P=0.0000);肺功能指标:第1秒用力呼气容积(65.23±11.65)%(t=3.8845,P=0.0000)、FEV1/FVC(93.61±4.14)(t=12.1382,P=0.0000)、FEV1(5.61±0.46)L(t=22.2251,P=0.0000);血气指标:动脉血二氧化碳分压(46.55±6.32)mmHg(t=10.2932,P=0.0000)、动脉血氧分压(73.94±6.61)mmHg(t=8.5933,P=0.0000)、pH(7.44±0.56)(t=12.7289,P=0.0000);住院天数:(15.78±3.42)d(t=10.7019,P=0.0000)、住院费用(5347.62±289.96)元(t=25.1564,P=0.0000)与对照组患者相比均差异有统计学意义(P<0.05)。结论接受无创呼吸机治疗的慢性阻塞性肺疾病急性加重期合并2型糖尿病患者,能够提升患者的临床治疗效果,改善患者的血气指标情况以及维持血糖值在合理的范围之内,并能够改善患者的肺功能,减少住院时间以及治疗费用。 Objective To summarize and analyze the clinical efficacy and safety of non-invasive ventilator in patients with acute exacerbation of chronic obstructive pulmonary disease and type 2 diabetes.Methods Fifty samples were analyzed for patients with acute exacerbation of chronic obstructive pulmonary disease and type 2 diabetes mellitus who were treated in our hospital from January 2017 to February 2018.All groups were treated by computerized method.The experimental group(n=25 cases)was treated with non-invasive ventilator,and the control group(n=25 cases)was treated routinely.The therapeutic effect and treatment safety of the two groups were compared.Results This experiment explored the blood glucose indexes of the patients in the experimental group:glycated hemoglobin(6.41±0.56)%(t=6.025 4,P=0.000 0),and postprandial blood glucose(6.21±1.44)mmol/L(t=6.087 2,P=0.000 0),fasting blood glucose(9.48±1.55)mmol/L(t=7.471 4,P=0.000 0);pulmonary function index:forced expiratory volume in the first second(65.23±11.65)%(t=3.884 5,P=0.000 0),FEV1/FVC(93.61±4.1 4)(t=12.138 2,P=0.000 0),FEV1(5.61±0.46)L(t=22.2251,P=0.0000);blood gas index:arterial blood carbon dioxide partial pressure(46.55±6.32)mmHg(t=10.293 2,P=0.000 0),arterial oxygen partial pressure(73.94±6.61)mmHg(t=8.593 3,P=0.000 0),pH(7.44±0.56)(t=12.728 9,P=0.000 0);hospitalization days:(15.78±3.42)days(t=10.701 9,P=0.000 0),hospitalization expenses(5 347.62±289.96)yuan(t=25.156 4,P=0.000 0)were compared with the control group,and the difference was statistically significant(P<0.05).Conclusion Patients with acute exacerbation of chronic obstructive pulmonary disease treated with non-invasive ventilator combined with type 2 diabetes can improve the clinical treatment of patients,improve the blood gas index of patients and maintain the blood glucose level within a reasonable range,and can improve patient's lung function and reduce hospital stay and treatment costs.
作者 马阿伟 齐慧 谭明思 肖红英 MA A-wei;QI Hui;TAN Ming-si;XIAO Hong-ying(Department of Respiratory Medicine,Third Division Hospital,Xinjiang Production and Construction Corps,Kashgar,Xinjiang,844000 China)
出处 《系统医学》 2019年第5期67-69,共3页
关键词 无创呼吸机 慢性阻塞性肺疾病 急性加重期合并2型糖尿病 效果 安全性 Non-invasive ventilator Chronic obstructive pulmonary disease Acute exacerbation with type 2 diabetes Effect Safety
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