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探讨地奥司明片在环状混合痔外切内扎术后肛缘水肿中的治疗效果 预览

The Therapeutic Effect of Diosmin Tablets on Anal Edema After External Excision and Internal Ligation of Circumferential Mixed Hemorrhoids
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摘要 目的:探究环状混合痔外切内扎术后使用地奥司明片对肛缘水肿的治疗效果。方法:选取2017年3月-2019年1月期间在我院行环状混合痔外切内扎术治疗的90例患者,按随机数字表法分成对照组(45例)与观察组(45例),对照组采取常规治疗,观察组在此基础上服用地奥司明片,比较两组术后肛缘水肿、视觉模拟评分法(Visualanaloguescale,VAS)、临床疗效及生活质量综合评估问卷表(GQOL-74)评分。结果:术后第1d,两组肛缘水肿评分、VAS评分相比,差异无统计学意义(P>0.05);术后第3d、第7d,观察组肛缘水肿评分、VAS评分均低于对照组,差异有统计学意义(P<0.05);观察组治疗总有效率高于对照组,差异有统计学意义(P<0.05);治疗后,观察组GQOLI274量表各维度评分均较对照组高,差异有统计学意义(P<0.05)。结论:环状混合痔外切内扎患者术后使用地奥司明片可有效消除肛缘水肿,减轻肛门疼痛,提高手术疗效,改善术后生活质量。 Objective: The purpose of this study was to investigate the treatment effect of Ostrin on the perianal edema after exonucleolysis. Methods: 90 patients with annular mixed hemorrhoid exonucleolysis in our hospital from March 2017 to January 2019 were divided into the control group (45 cases)and the observation group (45 cases)according to the random number table method, and the control group was treated with routine treatment. On the basis of the observation group, the group of Osmin was used to compare the postoperative perianal edema, the visual analogue scale (VAS), the clinical curative effect and the quality of life quality assessment questionnaire (GQOL-74). Results: Post-operative paragraph 1 On the 3rd and 7th day after operation, the scores of anal edema and VAS in the observation group were lower than those in the control group (P<0.05). There was no significant difference in anal edema score and VAS score between the two groups (P>0.05), but the difference was statistically significant on the 3rd and 7th day after operation (P<0.05). The total effective rate of treatment in the observation group was higher than that in the control group (P<0.05), and the scores of every dimension of GQOL I 274 in the observation group were higher than those in the control group (P<0.05), and there was a significant difference between the two groups (P<0.05).Conclusion: Diosmin tablets can effectively eliminate anal edema and relieve anal edema in patients with circumferential mixed hemorrhoids and internal ligation after operation. The pain of the door, the operation effect, and the quality of life after operation is improved.
作者 闵连永 MIN Lian-yong(Henan Xinyang central hospital,Xinyang Henan 464000,China)
出处 《药品评价》 CAS 2019年第8期44-46,共3页 Drug Evaluation
关键词 混合痔 环状混合痔外切内扎术 地奥司明片 肛缘水肿 Mixed Hemorrhoid Ring-like Mixed Hemorrhoid Exonucleolysis Olukast Tablet Perianal Edema
作者简介 闵连永,主要从事肛肠外科疾病的诊断与治疗工作。E-mail:272387923@qq.com.
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