Objective:To investigate the prognostic factors of elderly resectable hepatocellular carcinoma( HCC) with portal vein tumor thrombus. Methods: From January 2014 to June 2017,127 elderly patients with resectable hepatocellular carcinoma and portal vein tumor thrombus were selected as subjects. All patients underwent radical hepatectomy plus portal vein thrombectomy,portal vein cancer resection, right or left hepatectomy. All patients were followed up every six months by telephone or out-patient for survival until their deaths or until Au-gust 2018. The data included sex,differentiation,tumor diameter,tumor thrombus type,cirrhosis,AFP,postoperative TACE,intrahepatic me-tastasis,and tumor thrombus type. Results:At the end of the follow-up,42 patients survived and 85 died. There was no significant difference in sex,differentiation,tumor thrombus type and alpha fetoprotein between the two groups(P > 0. 05);low differentiation was more common in the death group than in the survival group,tumor diameter was more than 8 cm in the survival group,cirrhosis was more common in the survival group,postoperative TACE was more common in the survival group,intrahepatic metastasis was more common in the survival group,and infil-trating tumor thrombus was more common in the survival group(P < 0. 05). Multivariate analysis showed that low differentiation,tumor diame-ter≥8 cm,postoperative TACE,intrahepatic metastasis and invasive tumor thrombus were independent risk factors for prognosis of HCC with portal vein tumor thrombus. Conclusion:The prognosis of resectable hepatocellular carcinoma with portal vein tumor thrombus in elderly pa-tients is influenced by many factors,among which differentiation,direct tumor,postoperative TACE,intrahepatic metastasis and type of tumor thrombus are independent risk factors.
Chinese Journal of Integrated Traditonal and Western Medicine on Liver Diseases
portal vein tumor thrombus