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2013~2018年天津市津南区0~14岁儿童季节性甲型H1N1流感病原学监测分析 预览

Epidemiological Surveillance of Seasonal H1N1 Influenza in Children Aged 0-14 Years in Jinnan District of Tianjin from 2013 to 2018
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摘要 目的分析2013~2018年天津市津南区季节性甲型H1N1流感流行情况,为科学预防和控制流感提供依据。方法选择咸水沽医院作为监测哨点医院,采集2013年4月1日~2018年3月31日0~14岁儿童流感样病例(ILI)的咽拭子标本,采用实时荧光定量RT-PCR方法检测季节性甲型H1N1流感病毒核酸,以每年4月1日至次年3月31日为监测周期进行统计分析。结果5个监测周期采集ILI咽拭子标本分别为588、601、609、591和583份,季节性甲型H1N1流感病毒阳性率分别为9.69%、0、7.39%、10.15%和12.35%,阳性率比较,差异有统计学意义(P<0.05)。5个监测周期中有4个季节性甲型H1N1流感流行期,分别为2013年12月~2014年1月、2016年1~3月、2017年2~3月和2018年1~2月,2014年3月~2015年12月阳性病例数为0。按照年龄分为0~2岁、3~5岁、6~8岁、9~11岁和12~14岁5个年龄组,阳性率分别为3.15%、9.98%、11.08%、8.52%和5.98%,各年龄组之间阳性率比较,差异无统计学意义(P>0.05)。不同性别人群的季节性甲型H1N1流感阳性率差异无统计学意义(P>0.05)。结论季节性甲型H1N1流感病毒呈现出季节性流行的特点,流行期一般在冬春季,高峰期出现在1月份左右,3~8岁年龄儿童阳性病例数量最多,为易感人群。为更好防控流感,及时掌握流行趋势,仍需加强监测。 Objective To analyze the epidemic situation of seasonal H1N1 influenza in Jinnan District of Tianjin from 2013 to 2018, and provide evidence for scientific prevention and control of influenza. Methods The Xianshuigu Hospital was selected as a monitoring sentinel hospital to collect throat swab specimens from children aged 0-14 years (ILI) from April 1, 2013 to March 31, 2018. Real-time quantitative RT-PCR was used. The seasonal influenza A H1N1 influenza virus nucleic acid was detected and analyzed statistically from April 1 to March 31 of the following year. Results The ILI throat swab specimens collected during the five monitoring cycles were 588, 601, 609, 591 and 583, respectively. The positive rates of seasonal influenza A H1N1 influenza viruses were 9.69%, 0,7.39%, 10.15% and 12.35%, respectively,the difference was statistically significant(P< 0.05). There are 4 seasonal influenza A H1N1 influenza epidemics in the 5 monitoring cycles, from December 2013 to January 2014, January to March 2016, February to March 2017, and January 2018. In February, the number of positive cases from March 2014 to December 2015 was zero. According to the age, the age groups were 0~2 years old, 3~5 years old, 6~8 years old, 9~11 years old and 12~14 years old. The positive rates were 3.15%, 9.98%, 11.08%, 8.52% and 5.98% respectively, the positive rate between each age group was compared, the difference was not statistically significant (P>0.05). There was no significant difference in the positive rate of seasonal H1N1 flu among different gender groups (P>0.05).Conclusion The seasonal influenza A (H1N1) virus is characterized by seasonal epidemic. The epidemic period is generally in winter and spring, and the peak period is around January. The number of positive cases in children aged 3 to 8 years old is the most susceptible. In order to better prevent and control the flu and grasp the fashion trends in a timely manner, it is still necessary to strengthen monitoring.
作者 郑梅 王志鹏 孙雅娜 赵文 刘坚龄 杨振河 ZHENG Mei;WANG Zhi-peng;SUN Ya-na;ZHAO Wen;LIU Jian-ling;YANG Zhen-he(Department of Clinical Laboratory,Tianjin Jinnan District Center for Disease Control and Prevention, Tianjin 300000,China)
出处 《医学信息》 2019年第12期142-143,共2页 Medical Information
关键词 季节性甲型H1N1 流感 病原学 实时荧光定量PCR Seasonal H1N1 Influenza Pathogen Real-time PCR
作者简介 郑梅(1981.4-),女,吉林洮南人,硕士研究生,初级检验师,主要从事流感病毒方面的研究.
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