Objective To examine the state of restenosis after cerebrovascular stent implantation and the possible factors that contribute to the disease. Methods Firstly, the clinical data of 100 patients having undergone cerebrovascular stent implantation were subjected to retrospective analysis. Follow-ups were then conducted for one year. Then subjects were then divided into two groups, namely, restenosis group (in which restenosis was identified) and no restenosis group (in which restenosis was not found after operation). The factors that gave rise to the disease were lastly examined. Results 9%(9/100) of the patients were found to have vascular restenosis during the follow-ups. Statistically significant differences were found between the two groups in age, the rates of smoking habit, incidence of diabetes, incidence of coronary heart disease, incidence of hypertension, incidence of hyperlipemia and regular anticoagulant medication ( P <0.05). Multivariate logistic regression analysis showed that smoking ( OR =8.304), diabetes ( OR =5.082), coronary heart disease ( OR =5.269), hypertension ( OR =7.914), and hyperlipemia ( OR =4.971) were the risk factors that contributed to restenosis after surgery of cerebrovascular stent implantation ( P <0.05). Conclusions Smoking, diabetes, coronary heart disease, hypertension, and hyperlipemia increase the occurrence of restenosis after cerebrovascular stent implantation and therefore should be closely monitored and treated in clinical practice.