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中国中老年人群慢性病现状调查与共病关联分析

Investigation and association analysis of multimorbidity in middle-aged and elderly population in China
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摘要 目的利用关联规则研究我国中老年人群慢性病共病模式,探索慢性病间的关联性和关联强度.方法采用中国健康与养老追踪调查(China health and retirement longitudinal study, CHARLS)2015年的数据,纳入我国9省市45岁以上中老年人患14种慢性病情况,利用R3.4.3软件中的Apriori算法对数据进行分析,挖掘慢性病共病情况.结果 17796名调查对象中,至少患有一种慢性病人数为12245(68.81%),同时患有两种及以上慢性病的人数为7321 (41.15%).在筛选出的关联规则中,按照支持度排序,最常见的三种慢性病共病模式为血脂异常和心脏病、糖尿病和血脂异常、哮喘和慢性肺部疾病,规则支持度分别为6.77%、5.27%、4.28%,规则置信度分别为34.38%、43.14%、70.81%.关联规则结果多项指向心脏病、血脂异常、慢性肺部疾病.75岁以上年龄组强关联规则最多.结论心脏病存在于多种共病模式中,应加强对其的筛查与预防.血脂异常与糖尿病、高血压具有强关联性,且男性患者更易共患血脂异常.随着年龄增长,慢性病共患更普遍更复杂. Objective To characterize the multimorbidity patterns of chronic diseases in middleaged and elderly people in China, and explore the correlation and intensity among chronic diseases by using association rules. Methods A total of 17 796 people over 45 years old from 9 provinces and cities in China were sampled and surveyed. The data were analyzed by Apriori algorithm in R3. 4. 3 software to investigate the multimorbidity of chronic diseases. Results Among total 17 796 respondents,the number of patients with at least one chronic disease was 12 245 ( 68. 81%),and the number of patients with two or more chronic diseases was 7 321 ( 41. 15%). Among the selected association rules,according to the ranking of support degree,the most common three chronic disease multimorbidities were dyslipidemia and heart disease,diabetes mellitus and dyslipidemia,asthma and chronic lung disease. The rule support was 6. 77%,5. 27%,4. 28%,and the rule confidence was 34. 38%,43. 14%,and 70. 81%,respectively. Multiple results of association rules pointed to heart disease. After screening,the greatest association rules were found in the age group over 75 years old. Conclusions Heart disease exists in a variety of chronic disease multimorbidity patterns. Screening and prevention measures should be strengthened. Dyslipidemia is strongly associated with diabetes and hypertension,and male patients are more vulnerable to suffer from dyslipidemia. Chronic diseases intend to be more common and complicated along with age increase.
作者 程杨杨 曹志 侯洁 张馨予 李书 王耀刚 CHENG Yang-yang;CAO Zhi;HOU Jie;ZHANG Xin-yu;Ll Shu;WANG Yao-gang(School of Public Health,Tianjin Medical University,Tianjin 300070,China;School of Basic Medical Sciences,Tianjin Medical University,Tianjin 300070,China)
出处 《中华疾病控制杂志》 CAS CSCD 北大核心 2019年第6期625-629,共5页 Chinese Journal of Disease Control and Prevention
基金 国家自然科学基金(91746205,71673199).
关键词 慢性病 共病 关联规则 Chronic diseases Multimorbidity Association rules
作者简介 通信作者:王耀刚,E-mail:wangyg@tmu.edu.cn.
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