Objective To investigate the clinical efficacy of LEEP knife in the diagnosis and treatment of cervical intraepithelial neoplasia (CIN) under the guidance of colposcopy. Methods From April 2014 to March 2019, Convenient select 70 patients with cervical intraepithelial neoplasia were enrolled in our hospital. All patients underwent laparoscopic LEEP knife surgery and histopathological diagnosis was performed. The intraoperative blood loss, operation time, wound healing time, and LEEP clinical treatment effect were recorded. The results of pathological histology and multi-point biopsy diagnosis under colposcopy were compared. Results Seventy patients completed the operation successfully. The intraoperative blood loss was (8.05±0.98)mL;the operation time was (4.86±1.47) min;the wound healing time was (6.92±0.21) weeks;the postoperative 2 months follow-up, cervical morphology 9 cases (12.86%) were abnormal, 61 cases (87.14%) were cured after the second operation, and the cervix was smooth and the shape returned to normal. The pathological diagnosis of chronic cervicitis by colposcopy was 80.00% higher than that of LEEP of 44.29%. The difference was statistically significant (χ^2=4.301, P=0.038). The proportions of CINⅠ, CINⅡ, and CIN Ⅲ in the pathological diagnosis of multi-point biopsy under colposcopy were 11.43%, 7.14%, and 1.43%, respectively, and LEEP was 17.14%. 12.86%, 5.71%, the difference was not statistically significant (χ^2=0.933, 1.270, 0.830, P=0.334, 0.260, 0.172). Conclusion The patients with cervical intraepithelial neoplasia underwent laparoscopic LEEP scalpel surgery, which can better remove the lesions, which can effectively avoid the diagnosis and treatment and over-treatment. It is worthy of clinical promotion.
China & Foreign Medical Treatment
Cervical intraepithelial neoplasia