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1992-2013年北京市乙型肝炎疫苗接种预防慢性乙型肝炎成本效益

Cost-benefit analysis of hepatitis B vaccination for preventing chronic hepatitis B in Beijing during 1992-2013
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摘要 目的测算北京市1992-2013年乙型肝炎(乙肝)疫苗(Hepatitis B vaccine,HepB)接种预防慢性乙肝的成本效益。方法运用上下法和分步模型法对北京市1992-2013年慢性乙肝的费用和效益进行测算。结果北京市1992-2013年慢性乙肝相关疾病的贴现后费用在3 469.36万元(1992年)-17 006.95万元(2006年)之间;HepB预防慢性乙肝疾病的总效益为67 486.41万元,各年在1 574.54万元(1992年)-5 756.76万元(2012年)之间;年均效益为3 067.56万元,年均增长率为5.37%。2007-2013年与1993-2006年相比增量效益成本比为2.58。结论北京市1992-2013年HepB接种对预防慢性乙肝相关疾病具有较好的成本效益。 Objective To estimate the costs and benefits of vaccination with hepatitis B vaccine(HepB) for preventing chronic hepatitis B in Beijing during 1992-2013. Methods We calculated costs and benefits of HepB vaccination in preventing chronic hepatitis B in Beijing during 1992-2013 using the upper and lower bound method and the step-bystep model method. Results Discounted costs of chronic hepatitis B related diseases in Beijing during 1992-2013 ranged 3 469.36(1992) to 17 006.95(2006) ten-thousand RMB by year. The total benefit of HepB vaccination in preventing chronic hepatitis B related diseases was 67 486.41 ten-thousand RMB, ranging f rom 1 574.54(1992) to 5 756.76(2012) ten-thousand RMB by year. The average annual benef it was 3 067.56 ten-thousand RMB, with an average annual growth of 5.37%. The incremental benef it-cost ratio of 2007-2013 versus 1993-2006 was 2.58. Conclusion HepB vaccination in Beijing during 1992-2013 showed a good and improving cost-benefit ratio for preventing chronic hepatitis B related diseases.
作者 王溪 袁淑婷 郭艺玮 吕敏 石学峰 Wang Xi;Yuan Shuting;Guo Yiwei;Lü Min;Shi Xuefeng(Management School,Beijing University of Chinese Medicine,Beijing 100029,China;Peking University Peoples Hospital,Beijing 100044,China;Beijing Municipal Center for Disease Control and Prevention,Beijing 100013,China)
出处 《中国疫苗和免疫》 北大核心 2019年第4期397-400,共4页 Chinese Journal of Vaccines and Immunization
基金 北京市科技计划课题(D161100002716005)。
关键词 乙型肝炎疫苗 预防接种 慢性乙型肝炎 成本 效益 Hepatitis B vaccine Vaccination Chronic hepatitis B Cost Benefit
作者简介 通信作者:石学峰,Email:shixuefeng981206@163.com;第一作者:王溪,Email:2397275827@qq.com。
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