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代谢组学在动物应激研究中的应用

Application of metabolomics in research on animal stress
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摘要 代谢组学是生物机体在病理生理、遗传、环境或行为的不同刺激下,对机体所产生代谢产物变化的研究,是生物领域研究中一种重要的研究手段,已在植物学、营养学、中药学、微生物学、临床疾病诊断等研究领域得到广泛应用。动物应激一直是畜牧行业关注的热点,许多因素可导致动物应激,常见的应激类型有冷应激、热应激、氧化应激、束缚应激、噪音应激、运输应激,还有不可预知的慢性应激等,这些应激均可对动物机体产生一定危害。目前,代谢组学也已应用于动物应激领域的研究,本文对代谢组学在动物的冷应激、热应激、氧化应激及束缚应激研究中的应用作一综述。 Metabolomics is a subject about the change of metabolite of organisms stimulated by pathophysiological,genetic,environmental or behavior factors,which is an important method for biological research,and has been widely applied in the fields of botany,nutrition,Chinese pharmacy,microbiology and clinical disease diagnosis.Animal stress is a hotpot which is paid attention in animal husbandry,including cold stress,heat stress,oxidative stress,restraint stress,noise stress,transport stress and unpredictable chronic stress,which is caused by multiple factors and has a certain extent of harm to animals.At present,metabolomics is also applied in the field of animal stress.This article describes the application of metabolomics in the researches on cold stress,heat stress,oxidative stress and restraint stress in animals.
作者 李文杰 连帅 王立鹏(综述) 杨焕民(审校) LI Wen-jie;LIAN Shuai;WANG Li-peng;YANG Huan-min(College of Animal Science and Technology,Heilongjiang Bayi Agricultural University,Daqing 163319,Heilongjiang Province,China)
出处 《中国生物制品学杂志》 CAS CSCD 2019年第4期482-484,488共4页 Chinese Journal of Bilogicals
关键词 代谢组学 冷应激 热应激 氧化应激 束缚应激 Metabolomics Cold stress Heat stress Oxidative stress Restraint stress
作者简介 通讯作者:杨焕民,E-mail:yanghuanmin@aliyun.com.
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