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米非司酮联合米索前列醇在孕10~16周稽留流产患者中的治疗效果 预览

Therapeutic Effect of Mifepristone Combined with Misoprostol in Patients with Missed Abortion at 10~16 Weeks of Pregnancy
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摘要 目的探讨米非司酮联合米索前列醇治疗孕10~16周稽留流产患者的疗效和安全性。方法 120例孕10~16周稽留流产患者随机分为干预组(米非司酮联合米索前列醇治疗, 60例)和常规组(戊酸雌二醇治疗, 60例),比较两组的疗效及药物不良反应。结果干预组患者的治疗总有效率显著高于常规组(93.33%vs.73.33%, P <0.05)。两组的不良反应发生率无统计学差异(P>0.05)。结论米索前列醇联合米非司酮治疗孕10~16周稽留流产患者具有显著的临床疗效和较高的用药安全性。 Objective To explore the therapeutic effect and safety of mifepristone combined with misoprostol in the treatment of patients with missed abortion at 10~16 weeks of pregnancy.Methods 120 cases of patients with missed abortion at 10~16 weeks of pregnancy were randomly divided into the intervention group(mifepristone combined with misoprostol treatment,n=60)and the routine group(estradiol valerate treatment,n=60).The therapeutic effects and adverse reactions of the two groups were compared.Results The total effective rate of treatment of intervention group was significantly higher than that of routine group(93.33%vs.73.33%,P<0.05).No statistical difference was found between two groups in the incidences of adverse reactions(P>0.05).Conclusions Mifepristone combined with misoprostol in the treatment of patients with missed abortion at 10~16 weeks of pregnancy has significant clinical therapeutic effect and high medication safety.
作者 刘颖玫 李锦燕 刘迎英 LIU Yingmei;LI Jinyan;LIU Yingying(Department of Obstetrics and Gynecology,Shijing People's Hospital of Baiyun District,Guangzhou 510430,China)
出处 《临床医学工程》 2019年第4期497-498,共2页 Clinical Medicine and Engineering
关键词 稽留流产 米非司酮 米索前列醇 疗效 安全性 Missed abortion Mifepristone Misoprostol Therapeutic effect Safety
作者简介 刘颖玫(1982-),女,广东广州人,本科学历,主治医师,研究方向:妇产科。
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