Objective To study the clinical manifestations, pathologic characteristics, imaging features, diagnosis and treatment of adenomas of extrahepatic bile duct.Methods Two cases of adenomas of extrahepatic bile duct in our hospital and 14 cases reported in the literatures were analyzed retrospectively.Results The patients’(male 5, female 11) mean age was 58.4 years (range 21-85). The main manifestations included jaundice ( n =11), abdominal pain ( n =8),fever ( n =6), dyspepsia ( n =4),body weight loss ( n =3) and clay colored stool ( n =1). The locations of tumors were in the left hepatic duct ( n =1), right hepatic duct ( n =3), hepatic common bile duct( n =3),the junction of cystic duct and common bile duct ( n =1),distal common bile duct ( n =8). The pathologic types were tubular adenomas ( n =5), papillary (villous) adenomas ( n =10),and mucous adenoma ( n =1). All the patients underwent surgical therapy. The tumors were identified by postoperative histopathologic examination.Conclusion It is difficult to correctly diagnose adenomas of extrahepatic bile duct before operation, because the clinical manifestations are usually atypical. The definite diagnosis should depend on histopathologic examination. It is the key to completely resect the tumors. Postoperative follow up should be done on regular basis.
Chinese Journal of Bases and Clinics In General Surgery